Identification and characterization of major stem cell identity regulators within the epidermis The epidermis contains a great variety of functionally and spatially distinct stem... Read More
Centrosomes in mammalian skin epithelial cell fate decisions How cell fate decisions are acquired in the skin epithelium, how they change during aging and... Read More
Role of MMP-14 in connective tissue homeostasis and tumour invasion Based on the results of the previous funding period we now want to understand... Read More
Role of collagen-binding integrin receptors for cellular communication and homeostasis in the skin This project aims at establishing whether and by which mechanisms integrin-mediated... Read More
Regulation of epidermal stratification and homeostasis through contractility and density sensing How the complex but stereotyped tissue structure of the mammalian epidermis is formed,... Read More
Mammalian polarity proteins in skin homeostasis and disease How cell morphology is coordinated in the context of an entire organ is an intriguing question... Read More
Regulation of epidermal morphogenesis and barrier function by intercellular junctions We have demonstrated that classical cadherins through regulation of intercellular junctions, the cytoskeleton and... Read More
Epithelial TNFR1 signalling in skin homeostasis and inflammation TNF is a critical pathogenic factor in psoriasis and other chronic inflammatory diseases, but the mechanisms... Read More
Hedgehog-Gli signalling in skin homeostasis and tumour formation Indian Hedgehog (Ihh) controls proliferation and differentiation of keratinocytes and prevents tumour progression and metastasis. Mechanistically,... Read More
November 2016 Scientists from the medical and natural science faculty of the University of Cologne, the University Hospital, the MPI for Biology of Ageing,... Read More
Durch die weitere Nutzung der Seite stimmst du der Verwendung von Cookies zu. Weitere Informationen
Die Cookie-Einstellungen auf dieser Website sind auf "Cookies zulassen" eingestellt, um das beste Surferlebnis zu ermöglichen. Wenn du diese Website ohne Änderung der Cookie-Einstellungen verwendest oder auf "Akzeptieren" klickst, erklärst du sich damit einverstanden.