Force generation and transmission in keloid fibroblasts: dissecting the role of mechanosensitive molecules in cell function

July 29, 2015A11 WICKSTRÖM

Schneider D, Wickström SA Exp. Dermatol. 2015 Aug;24(8):574-5 PMID: 25959359 Abstract

Correlation of Merkel cell polyomavirus positivity with PDGFR? mutations and survivin expression in Merkel cell carcinoma

July 27, 2015B4 ZIGRINO MAUCHBatinica M, Akgül B, Silling S, Mauch C, Zigrino P; J Dermatol Sci. 2015 Jul;79(1):43-9. doi: 10.1016/j.jdermsci.2015.04.002. Epub 2015 Apr 14.

Abstract BACKGROUND: Merkel cell carcinoma (MCC) is a neuroendocrine cancer of the skin postulated to originate through Merkel cell polyomavirus (MCPyV) oncogenesis and/or by... Read More

Par Proteins in Tumor Formation and Progression

July 14, 2015A10 IDEN

Mescher, M., and Iden, S. (2015). Cell Polarity 2. Role in Dev. and Dis. Springer 2, 344. Book chapter.

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

June 27, 2015B12 SENGLE

Sengle G, Carlberg V, Tufa SF, Charbonneau NL, Smaldone S, Carlson EJ, Ramirez F, Keene DR, Sakai LY PLoS Genet. 2015 Jun;11(6):e1005340 PMID: 26114882... Read More

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis

June 25, 2015A9 HAMMERSCHMIDTWestcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC; PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

Abstract Skin disorders are widespread, but available treatments are limited. A more comprehensive understanding of skin development mechanisms will drive identification of new treatment... Read More

Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells

June 24, 2015B13 FABRISommer A, Fabri M; PLoS One. 2015 Jun 24;10(6):e0130395. doi: 10.1371/journal.pone.0130395. eCollection 2015.

Abstract One central mechanism, by which vitamin D regulates human immune responses, is the direct modulation of dendritic cells (DCs). However, the effect of... Read More

Mildred Scheel Lectureship series meets “Cologne Cancer Club” and “Women in Science and Society”

June 20, 2015Good To Know

It was our pleasure to host the Mildred Scheel Lectureship given by Prof. Dr. Anne-Lise Børresen-Dale, University of Oslo, Norway. In cooperation with our... Read More

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature

June 13, 2015B14 DENZEL

Acevedo LM, Lindquist JN, Walsh BM, Sia P, Cimadamore F, Chen C, Denzel M, Pernia CD, Ranscht B, Terskikh A, Snyder EY, Cheresh DA... Read More

Vitamin D every day to keep the infection away?

June 3, 2015B13 FABRI

Kroner Jde C, Sommer A, Fabri M Nutrients 2015 Jun;7(6):4170-88 PMID: 26035244 Abstract Within the last decade, vitamin D has emerged as a central... Read More

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53

May 21, 2015publicationsDesantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M; Cell Death Dis. 2015 May 21;6:e1764. doi: 10.1038/cddis.2015.117.

Abstract The tumor suppressor p53 is mainly involved in the transcriptional regulation of a large number of growth-arrest- and apoptosis-related genes. However, a clear... Read More

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