publications

New specific HSP47 functions in collagen subfamily chaperoning

Köhler A, Mörgelin M, Gebauer JM, Öcal S, Imhof T, Koch M, Nagata K, Paulsson M, Zaucke F, Baumann U, Sengle G FASEB J...   Read More

Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

Dias Gomes M, Letzian S, Saynisch M, Iden S Nat Commun 2019 Jul;10(1):3362 PMID: 31358743 Abstract Epithelial homeostasis requires balanced progenitor cell proliferation and...   Read More

Dual role of laminin‑511 in regulating melanocyte migration and differentiation

Üstün Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, Krieg T Matrix Biol. 2018 Sep; PMID: 30273664 Abstract Laminins are the...   Read More

Fibrillin microfibrils and proteases, key integrators of fibrotic pathways

Zigrino P, Sengle G Adv. Drug Deliv. Rev. 2018 Apr; PMID: 29709492 Abstract Supramolecular networks composed of multi-domain ECM proteins represent intricate cellular microenvironments...   Read More

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo...   Read More

Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER

Lockhart-Cairns MP, Lim KTW, Zuk A, Godwin ARF, Cain SA, Sengle G, Baldock C Matrix Biol. 2019 04;77:73-86 PMID: 30125619 Abstract Bone morphogenetic proteins...   Read More

Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition

Gräb J, Suárez I, van Gumpel E, Winter S, Schreiber F, Esser A, Hölscher C, Fritsch M, Herb M, Schramm M, Wachsmuth L, Pallasch...   Read More

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

Koliaraki V, Chalkidi N, Henriques A, Tzaferis C, Polykratis A, Waisman A, Muller W, Hackam DJ, Pasparakis M, Kollias G Cell Rep 2019 Jan;26(3):536-545.e4...   Read More

RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke...   Read More

RIP Kinases in Liver Cell Death, Inflammation and Cancer

Kondylis V, Pasparakis M Trends Mol Med 2019 Jan;25(1):47-63 PMID: 30455045 Abstract Cell death is intrinsically linked to inflammatory liver disease and cancer development....   Read More

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