publications

Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

Dias Gomes M, Letzian S, Saynisch M, Iden S Nat Commun 2019 Jul;10(1):3362 PMID: 31358743 Abstract Epithelial homeostasis requires balanced progenitor cell proliferation and...   Read More

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo...   Read More

The Pain Dynamics of Small Fiber Neuropathy

Brouwer BA, van Kuijk SMJ, Bouwhuis A, Faber CG, van Kleef M, Merkies ISJ, Hoeijmakers JGJ J Pain 2018 Dec; PMID: 30529697 Abstract Pain...   Read More

DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1

Ribeiro-Silva C, Aydin ÖZ, Mesquita-Ribeiro R, Slyskova J, Helfricht A, Marteijn JA, Hoeijmakers JHJ, Lans H, Vermeulen W Nat Commun 2018 10;9(1):4067 PMID: 30287812...   Read More

Expression of pathogenic SCN9A mutations in the zebrafish: A model to study small-fiber neuropathy

Eijkenboom I, Sopacua M, Otten ABC, Gerrits MM, Hoeijmakers JGJ, Waxman SG, Lombardi R, Lauria G, Merkies ISJ, Smeets HJM, Faber CG, Vanoevelen JM,...   Read More

DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones

Mandemaker IK, Geijer ME, Kik I, Bezstarosti K, Rijkers E, Raams A, Janssens RC, Lans H, Hoeijmakers JH, Demmers JA, Vermeulen W, Marteijn JA...   Read More

Nuclear Genomic Instability and Aging

Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD Annu. Rev. Biochem. 2018 06;87:295-322 PMID: 29925262 Abstract The nuclear genome decays...   Read More

Mystery Case: Superior oblique myokymia: An uncommon cause of intermittent diplopia

Joosten IBT, Hoeijmakers JGJ Neurology 2018 Feb;90(9):e814 PMID: 29483324 Abstract

Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model

La Fata G, van Vliet N, Barnhoorn S, Brandt RMC, Etheve S, Chenal E, Grunenwald C, Seifert N, Weber P, Hoeijmakers JHJ, Mohajeri MH,...   Read More

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway

Mandemaker IK, van Cuijk L, Janssens RC, Lans H, Bezstarosti K, Hoeijmakers JH, Demmers JA, Vermeulen W, Marteijn JA Sci Rep 2017 Nov;7(1):15353 PMID:...   Read More

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