A1 NIESSEN

Epithelial polarity limits EMT

Persa OD, Niessen CM Nat. Cell Biol. 2019 Mar;21(3):299-300 PMID: 30824839 Abstract Epithelial–mesenchymal transition (EMT) is crucial for development, and for dissemination and invasion...   Read More

Hepatitis B virus promotes β-catenin-signalling and disassembly of adherens junctions in a Src kinase dependent fashion

von Olshausen G, Quasdorff M, Bester R, Arzberger S, Ko C, van de Klundert M, Zhang K, Odenthal M, Ringelhan M, Niessen CM, Protzer...   Read More

Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation

Noethel B, Ramms L, Dreissen G, Hoffmann M, Springer R, Rübsam M, Ziegler WH, Niessen CM, Merkel R, Hoffmann B Mol. Biol. Cell 2018...   Read More

E-cadherin binds to desmoglein to facilitate desmosome assembly

Shafraz O, Rübsam M, Stahley SN, Caldara AL, Kowalczyk AP, Niessen CM, Sivasankar S Elife 2018 07;7 PMID: 29999492 Abstract Desmosomes are adhesive junctions...   Read More

AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer

Welcker D, Jain M, Khurshid S, Jokić M, Höhne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Büttner R,...   Read More

Cell adhesion and mechanics as drivers of tissue organization and differentiation: local cues for large scale organization

Wickström SA, Niessen CM Curr. Opin. Cell Biol. 2018 10;54:89-97 PMID: 29864721 Abstract Biological patterns emerge through specialization of genetically identical cells to take...   Read More

Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis

Vorhagen S, Kleefisch D, Persa OD, Graband A, Schwickert A, Saynisch M, Leitges M, Niessen CM, Iden S Oncogene 2018 09;37(37):5136-5146 PMID: 29789715 Abstract...   Read More

Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification

Miroshnikova YA, Le HQ, Schneider D, Thalheim T, Rübsam M, Bremicker N, Polleux J, Kamprad N, Tarantola M, Wang I, Balland M, Niessen CM,...   Read More

Imbalance of Mitochondrial Respiratory Chain Complexes in the Epidermis Induces Severe Skin Inflammation

Weiland D, Brachvogel B, Hornig-Do HT, Neuhaus JFG, Holzer T, Tobin DJ, Niessen CM, Wiesner RJ, Baris OR J. Invest. Dermatol. 2017 Aug; PMID:...   Read More

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning

Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M,...   Read More

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