A11 WICKSTRÖM

Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny

Chacón-Martínez CA, Klose M, Niemann C, Glauche I, Wickström SA EMBO J. 2017 Jan;36(2):151-164 PMID: 27940653 Abstract Understanding how complex tissues are formed, maintained,...   Read More

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

Le HQ, Ghatak S, Yeung CY, Tellkamp F, Günschmann C, Dieterich C, Yeroslaviz A, Habermann B, Pombo A, Niessen CM, Wickström SA Nat. Cell...   Read More

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells

A11 WICKSTRÖMpublicationsMorgner J, Ghatak S, Jakobi T, Dieterich C, Aumailley M, Wickström SA; Nat Commun. 2015 Sep 8;6:8198. doi: 10.1038/ncomms9198.

Abstract Stem cells reside in specialized niches that are critical for their function. Quiescent hair follicle stem cells (HFSCs) are confined within the bulge...   Read More

Force generation and transmission in keloid fibroblasts: dissecting the role of mechanosensitive molecules in cell function

Schneider D, Wickström SA Exp. Dermatol. 2015 Aug;24(8):574-5 PMID: 25959359 Abstract

Role of integrin signalling through integrin-linked kinase in skin physiology and pathology

Eckes B, Krieg T, Wickström SA Exp. Dermatol. 2014 Jul;23(7):453-6 PMID: 24773528 Abstract Cell-matrix adhesions provide structural stability to the tissue and regulate intracellular...   Read More

The weakest link: a new paradigm for stabilizing the integrin-actin connection

Morgner J, Wickström SA Cell Cycle 2013 Sep;12(18):2929-30 PMID: 23974089 Abstract

The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165

A11 WICKSTRÖMpublicationsTraub S, Morgner J, Martino MM, Höning S, Swartz MA, Wickström SA, Hubbell JA, Eming SA; Biomaterials. 2013 Aug;34(24):5958-68. doi: 10.1016/j.biomaterials.2013.04.050. Epub 2013 May 14.

Abstract   Synergy in the downstream signaling pathways of the vascular endothelial growth factor receptor-2 (VEGFR-2) and the integrin αvβ3 is critical for blood...   Read More

ILK: a pseudokinase with a unique function in the integrin-actin linkage

Ghatak S, Morgner J, Wickström SA Biochem. Soc. Trans. 2013 Aug;41(4):995-1001 PMID: 23863169 Abstract ILK (integrin-linked kinase) is a central component of cell-matrix adhesions...   Read More

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

A11 WICKSTRÖMB3 ECKES KRIEGpublications Radovanac K, Morgner J, Schulz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA; EMBO J. 2013 May 15;32(10):1409-24. doi: 10.1038/emboj.2013.90. Epub 2013 Apr 23.

Abstract   Integrin-linked kinase (ILK) is an adaptor protein required to establish and maintain the connection between integrins and the actin cytoskeleton. This linkage...   Read More

Genetic analyses of integrin signaling

A11 WICKSTRÖMpublicationsWickström, S., Radovanac, K., Fässler, R., Cold Spring Harb Perspect Biol. 2011 Feb 1;3(2). pii: a005116. doi: 10.1101/cshperspect.a005116

Abstract   The development of multicellular organisms, as well as maintenance of organ architecture and function, requires robust regulation of cell fates. This is...   Read More

© 2017 SFB 829