A11 WICKSTRÖM

Signaling in the stem cell niche: regulating cell fate, function and plasticity

Chacón-Martínez CA, Koester J, Wickström SA Development 2018 08;145(15) PMID: 30068689 Abstract Stem cells have the ability to self-renew and differentiate along multiple lineages,...   Read More

Cell adhesion and mechanics as drivers of tissue organization and differentiation: local cues for large scale organization

Wickström SA, Niessen CM Curr. Opin. Cell Biol. 2018 10;54:89-97 PMID: 29864721 Abstract Biological patterns emerge through specialization of genetically identical cells to take...   Read More

Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification

Miroshnikova YA, Le HQ, Schneider D, Thalheim T, Rübsam M, Bremicker N, Polleux J, Kamprad N, Tarantola M, Wang I, Balland M, Niessen CM,...   Read More

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

Nüchel J, Ghatak S, Zuk AV, Illerhaus A, Mörgelin M, Schönborn K, Blumbach K, Wickström SA, Krieg T, Sengle G, Plomann M, Eckes B...   Read More

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning

Rübsam M, Mertz AF, Kubo A, Marg S, Jüngst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M,...   Read More

Adherens Junctions and Desmosomes Coordinate Mechanics and Signaling to Orchestrate Tissue Morphogenesis and Function: An Evolutionary Perspective

Rübsam M, Broussard JA, Wickström SA, Nekrasova O, Green KJ, Niessen CM Cold Spring Harb Perspect Biol 2017 Sep; PMID: 28893859 Abstract Cadherin-based adherens...   Read More

Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny

Chacón-Martínez CA, Klose M, Niemann C, Glauche I, Wickström SA EMBO J. 2017 Jan;36(2):151-164 PMID: 27940653 Abstract Understanding how complex tissues are formed, maintained,...   Read More

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

Le HQ, Ghatak S, Yeung CY, Tellkamp F, Günschmann C, Dieterich C, Yeroslaviz A, Habermann B, Pombo A, Niessen CM, Wickström SA Nat. Cell...   Read More

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells

A11 WICKSTRÖMpublicationsMorgner J, Ghatak S, Jakobi T, Dieterich C, Aumailley M, Wickström SA; Nat Commun. 2015 Sep 8;6:8198. doi: 10.1038/ncomms9198.

Abstract Stem cells reside in specialized niches that are critical for their function. Quiescent hair follicle stem cells (HFSCs) are confined within the bulge...   Read More

Force generation and transmission in keloid fibroblasts: dissecting the role of mechanosensitive molecules in cell function

Schneider D, Wickström SA Exp. Dermatol. 2015 Aug;24(8):574-5 PMID: 25959359 Abstract

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