A13 RADA-IGLESIAS

Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations

Irmak D, Fatima A, Gutiérrez-Garcia R, Rinschen MM, Wagle P, Altmüller J, Arrigoni L, Hummel B, Klein C, Frese CK, Sawarkar R, Rada-Iglesias A,...   Read More

Pioneering of Enhancer Landscapes during Pluripotent State Transitions

Rada-Iglesias A Cell Stem Cell 2018 Aug;23(2):149-151 PMID: 30075122 Abstract The transitions between different pluripotency states are regulated by large changes in enhancer landscapes....   Read More

Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation

Fueyo R, Iacobucci S, Pappa S, Estarás C, Lois S, Vicioso-Mantis M, Navarro C, Cruz-Molina S, Reyes JC, Rada-Iglesias Á, de la Cruz X,...   Read More

Is H3K4me1 at enhancers correlative or causative?

Rada-Iglesias A Nat. Genet. 2018 Jan;50(1):4-5 PMID: 29273804 Abstract

Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation

Rada-Iglesias A Mol. Syst. Biol. 2017 10;13(10):950 PMID: 29061670 Abstract

Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples

Rehimi R, Bartusel M, Solinas F, Altmüller J, Rada-Iglesias A J Vis Exp 2017 08;(126) PMID: 28872116 Abstract Chromatin immunoprecipitation (ChIP) is a widely-used...   Read More

GARLIC: a bioinformatic toolkit for aetiologically connecting diseases and cell type-specific regulatory maps

Nikolic M, Papantonis A, Rada-Iglesias A Hum. Mol. Genet. 2017 02;26(4):742-752 PMID: 28007912 Abstract Genome-wide association studies (GWAS) have emerged as a powerful tool...   Read More

Epigenomics-Based Identification of Major Cell Identity Regulators within Heterogeneous Cell Populations

Rehimi R, Nikolic M, Cruz-Molina S, Tebartz C, Frommolt P, Mahabir E, Clément-Ziza M, Rada-Iglesias A Cell Rep 2016 12;17(11):3062-3076 PMID: 27974217 Abstract Cellular...   Read More

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation

Cruz-Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, van Ijcken WFJ, Grosveld F, Frommolt P, Bazzi H, Rada-Iglesias A Cell...   Read More

Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification

Respuela P, Nikolić M, Tan M, Frommolt P, Zhao Y, Wysocka J, Rada-Iglesias A Cell Stem Cell 2016 Jan;18(1):118-33 PMID: 26748758 Abstract Following implantation,...   Read More

  • Upcoming Events

    1. “Collagen secretion in Health and Disease”

      June 26 @ 5:15 pm - 6:15 pm
    2. Women in Science and Society lecture with Prof. Susan E Quaggin

      July 1 @ 12:30 pm - 7:00 pm
    3. 4th Connector Meeting

      September 6 @ 3:00 pm - 6:30 pm
    4. 5th Connector Meeting

      November 8 @ 3:00 pm - 6:00 pm

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