Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification

January 11, 2016A13 RADA-IGLESIAS

Respuela P, Nikolić M, Tan M, Frommolt P, Zhao Y, Wysocka J, Rada-Iglesias A Cell Stem Cell 2016 Jan;18(1):118-33 PMID: 26748758 Abstract Following implantation,... Read More

Genetic variation within transcriptional regulatory elements and its implications for human disease

November 4, 2014A13 RADA-IGLESIAS publications

Rada-Iglesias A Biol. Chem. 2014 Dec;395(12):1453-60 PMID: 25205712 Abstract Common human pathologies have a complicated etiology involving both genetic and environmental risk factors. Moreover,... Read More

Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

November 5, 2012A13 RADA-IGLESIAS publications

Rada-Iglesias A, Bajpai R, Prescott S, Brugmann SA, Swigut T, Wysocka J Cell Stem Cell 2012 Nov;11(5):633-48 PMID: 22981823 Abstract Neural crest cells (NCC)... Read More

Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease

November 15, 2011A13 RADA-IGLESIAS publications

Rada-Iglesias A, Wysocka J Genome Med 2011 Jun;3(6):36 PMID: 21658297 Abstract Human pluripotent cells such as human embryonic stem cells (hESCs) and induced pluripotent... Read More

A unique chromatin signature uncovers early developmental enhancers in humans

February 10, 2011A13 RADA-IGLESIAS publications

Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J Nature 2011 Feb;470(7333):279-83 PMID: 21160473 Abstract Cell-fate transitions involve the integration of... Read More

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A13 RADA-IGLESIAS

Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification

Genetic variation within transcriptional regulatory elements and its implications for human disease

Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease

A unique chromatin signature uncovers early developmental enhancers in humans

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