A14 WIESNER

Imbalance of Mitochondrial Respiratory Chain Complexes in the Epidermis Induces Severe Skin Inflammation

Weiland D, Brachvogel B, Hornig-Do HT, Neuhaus JFG, Holzer T, Tobin DJ, Niessen CM, Wiesner RJ, Baris OR J. Invest. Dermatol. 2017 Aug; PMID:...   Read More

Correction: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

Kumar V, Bouameur JE, Bär J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P,...   Read More

Catecholamine Metabolism Induces Mitochondrial DNA Deletions and Leads to Severe Adrenal Degeneration during Aging

Neuhaus JF, Baris OR, Kittelmann A, Becker K, Rothschild MA, Wiesner RJ Neuroendocrinology 2017;104(1):72-84 PMID: 26895241 Abstract BACKGROUND: Aging is a multifactorial process characterized...   Read More

Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging

Baris OR, Ederer S, Neuhaus JF, von Kleist-Retzow JC, Wunderlich CM, Pal M, Wunderlich FT, Peeva V, Zsurka G, Kunz WS, Hickethier T, Bunck...   Read More

Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions

A14 WIESNERA3 NIEMANNpublicationsKloepper JE, Baris OR, Reuter K, Kobayashi K, Weiland D, Vidali S, Tobin DJ, Niemann C, Wiesner RJ, Paus R; J Invest Dermatol. 2015 Mar;135(3):679-89. doi: 10.1038/jid.2014.475. Epub 2014 Nov 5.

Abstract Here, we studied how epithelial energy metabolism impacts overall skin development by selectively deleting intraepithelial mtDNA in mice by ablating a key maintenance...   Read More

Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing

Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M,...   Read More

Catecholamine metabolism drives generation of mitochondrial DNA deletions in dopaminergic neurons

Neuhaus JF, Baris OR, Hess S, Moser N, Schröder H, Chinta SJ, Andersen JK, Kloppenburg P, Wiesner RJ Brain 2014 Feb;137(Pt 2):354-65 PMID: 24163249...   Read More

Nonsense mutations in the COX1 subunit impair the stability of respiratory chain complexes rather than their assembly

Hornig-Do HT, Tatsuta T, Buckermann A, Bust M, Kollberg G, Rötig A, Hellmich M, Nijtmans L, Wiesner RJ EMBO J. 2012 Mar;31(5):1293-307 PMID: 22252130...   Read More

The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells

Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JF, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T,...   Read More

Clonal expansion of different mtDNA variants without selective advantage in solid tumors

Gekeler J, Zsurka G, Kunz WS, Preuss SF, Klussmann JP, Guntinas-Lichius O, Wiesner RJ Mutat. Res. 2009 Mar;662(1-2):28-32 PMID: 19114048 Abstract In search of...   Read More

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