Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging

Edifizi D, Schumacher B Int J Mol Sci 2017 Nov;18(11) PMID: 29113067 Abstract DNA damage causally contributes to aging and age-related diseases. The declining...   Read More

DNA damage responses and p53 in the aging process

Ou HL, Schumacher B Blood 2017 Nov; PMID: 29141944 Abstract The genome is constantly attacked by genotoxic insults. DNA damage has long been established...   Read More

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans

Wilson DM, Rieckher M, Williams AB, Schumacher B Nucleic Acids Res. 2017 Sep;45(16):9467-9480 PMID: 28934497 Abstract DNA interstrand crosslinks (ICLs) are generated by endogenous...   Read More

Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans

Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger M, Schumacher B Cell Rep 2017 Aug;20(9):2026-2043 PMID: 28854356 Abstract DNA...   Read More

A simple answer to complex questions: Caenorhabditis elegans as an experimental model for examining the DNA damage response and disease genes

Rieckher M, Bujarrabal A, Doll MA, Soltanmohammadi N, Schumacher B J. Cell. Physiol. 2017 May; PMID: 28463453 Abstract The genetic information is constantly challenged...   Read More

E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis

Ackermann L, Schell M, Pokrzywa W, Kevei É, Gartner A, Schumacher B, Hoppe T Nat. Struct. Mol. Biol. 2016 Nov;23(11):995-1002 PMID: 27669035 Abstract Multiple...   Read More

p53 in the DNA-Damage-Repair Process

Williams AB, Schumacher B Cold Spring Harb Perspect Med 2016;6(5) PMID: 27048304 Abstract The cells in the human body are continuously challenged by a...   Read More

A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA

Babu V, Schumacher B DNA Repair (Amst.) 2016 May;41:8-15 PMID: 27043179 Abstract The transcription-coupled repair pathway (TC-NER) plays a vital role in removing transcription-blocking...   Read More

Systemic DNA damage responses in aging and diseases

Ribezzo F, Shiloh Y, Schumacher B Semin. Cancer Biol. 2016 Jan; PMID: 26773346 Abstract The genome is constantly attacked by a variety of genotoxic...   Read More

Longevity through DNA damage tolerance

A7 SCHUMACHERpublicationsCastells-Roca L, Mueller MM, Schumacher B; Cell Cycle. 2015;14(4):467-8. doi: 10.1080/15384101.2015.1006543.


  • Upcoming Events

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      Mai 16 - Mai 18
    2. Women in Science and Society with Sarah Millar

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      August 31 @ 3:00 pm - 5:30 pm
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      November 12 - November 14

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