A7 SCHUMACHER

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C,...   Read More

Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice

Habermehl TL, Parkinson KC, Hubbard GB, Ikeno Y, Engelmeyer JI, Schumacher B, Mason JB Geroscience 2019 02;41(1):25-38 PMID: 30547325 Abstract Cardiovascular disease, rare in...   Read More

BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in

Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N...   Read More

Tracking senescent cells: A new biomarker assay opens new avenues in senescence research

Bujarrabal A, Schumacher B Mech. Ageing Dev. 2017 03;162:106-107 PMID: 28161355 Abstract

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC,...   Read More

The tumour suppressor CYLD regulates the p53 DNA damage response

Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M Nat Commun...   Read More

MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO

Bianco JN, Schumacher B Nucleic Acids Res. 2018 Jul;46(12):6129-6139 PMID: 29788264 Abstract Ultraviolet (UV) induces distorting lesions to the DNA that can lead to...   Read More

Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans

Rieckher M, Markaki M, Princz A, Schumacher B, Tavernarakis N Cell Rep 2018 Oct;25(1):199-211.e6 PMID: 30282029 Abstract Aging is accompanied by a pervasive collapse...   Read More

The Cdkn1a Mouse as a Tool to Study p53-Mediated Tumor Suppression

Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F,...   Read More

Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging

Edifizi D, Schumacher B Int J Mol Sci 2017 Nov;18(11) PMID: 29113067 Abstract DNA damage causally contributes to aging and age-related diseases. The declining...   Read More

  • Upcoming Events

    1. 4th Connector Meeting

      September 6 @ 3:00 pm - 6:30 pm
    2. 5th Connector Meeting

      November 8 @ 3:00 pm - 6:00 pm

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