B12 SENGLE

Fibrillin microfibrils and proteases, key integrators of fibrotic pathways

June 5, 2019B12 SENGLE B4 ZIGRINO MAUCH

Zigrino P, Sengle G Adv. Drug Deliv. Rev. 2018 Apr; PMID: 29709492 Abstract Supramolecular networks composed of multi-domain ECM proteins represent intricate cellular microenvironments... Read More

Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER

April 16, 2019B12 SENGLE

Lockhart-Cairns MP, Lim KTW, Zuk A, Godwin ARF, Cain SA, Sengle G, Baldock C Matrix Biol. 2019 04;77:73-86 PMID: 30125619 Abstract Bone morphogenetic proteins... Read More

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis

March 7, 2019B12 SENGLE

Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR Eur. Respir.... Read More

ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome

November 1, 2018B12 SENGLE

Mularczyk EJ, Singh M, Godwin ARF, Galli F, Humphreys N, Adamson AD, Mironov A, Cain SA, Sengle G, Boot-Handford RP, Cossu G, Kielty CM,... Read More

Identification of antibodies against extracellular matrix proteins in human osteoarthritis

September 10, 2018B12 SENGLE

Ruthard J, Hermes G, Hartmann U, Sengle G, Pongratz G, Ostendorf B, Schneider M, Höllriegl S, Zaucke F, Wagener R, Streichert T, Klatt AR... Read More

Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program

July 15, 2018B12 SENGLE B3 ECKES KRIEG B7 EMING

Do NN, Willenborg S, Eckes B, Jüngst C, Sengle G, Zaucke F, Eming SA J. Immunol. 2018 Jul;201(2):663-674 PMID: 29898959 Abstract Myeloid cells can... Read More

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

January 3, 2018A11 WICKSTRÖM B12 SENGLE B3 ECKES KRIEG

Nüchel J, Ghatak S, Zuk AV, Illerhaus A, Mörgelin M, Schönborn K, Blumbach K, Wickström SA, Krieg T, Sengle G, Plomann M, Eckes B... Read More

Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development

October 31, 2017B12 SENGLE

Vallecillo-García P, Orgeur M, Vom Hofe-Schneider S, Stumm J, Kappert V, Ibrahim DM, Börno ST, Hayashi S, Relaix F, Hildebrandt K, Sengle G, Koch... Read More

Fibulin-4 deposition requires EMILIN-1 in the extracellular matrix of osteoblasts

July 7, 2017B12 SENGLE

Schiavinato A, Keene DR, Imhof T, Doliana R, Sasaki T, Sengle G Sci Rep 2017 Jul;7(1):5526 PMID: 28717224 Abstract Tissue microenvironments formed by extracellular... Read More

Raman microspectroscopy as a diagnostic tool for the non-invasive analysis of fibrillin-1 deficiency in the skin and in the in vitro skin models

April 2, 2017B12 SENGLE

Brauchle E, Bauer H, Fernes P, Zuk A, Schenke-Layland K, Sengle G Acta Biomater 2017 Apr;52:41-48 PMID: 27956365 Abstract Fibrillin microfibrils and elastic fibers... Read More