Home  |  publications  |  B12 SENGLE  |  Page 4

B12 SENGLE

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites

B12 SENGLEOno, R.N., Sengle, G., Charbonneau, N.L., Carlberg, V., Bächinger, H.P., Sasaki, T., Lee-Arteaga, S., Zilberberg, L., Rifkin, D.B., Ramirez, F., Chu, M.L., and Sakai, L.Y., J Biol Chem. 2009 Jun 19;284(25):16872-81. doi: 10.1074/jbc.M809348200. Epub 2009 Apr 6.

Abstract Latent transforming growth factor (TGF) beta-binding proteins (LTBPs) interact with fibrillin-1. This interaction is important for proper sequestration and extracellular control of TGFbeta....   Read More

A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7

B12 SENGLESengle, G., Ono, R., Lyons, K.M., Bächinger, H.P., and Sakai, L.Y., J Mol Biol. 2008 Sep 12;381(4):1025-39. doi: 10.1016/j.jmb.2008.06.074. Epub 2008 Jul 2.

Abstract Bone morphogenetic proteins (BMPs) are morphogens with long-range signaling activities. BMP-7 is secreted as a stable complex consisting of a growth factor noncovalently...   Read More

Targeting of bone morphogenetic protein growth factor complexes to fibrillin

B12 SENGLE Sengle, G., Charbonneau, N.L., Ono, R.N., Sasaki, T., Alvarez, J., Keene, D.R., Bächinger H.P., and Sakai, L.Y., J Biol Chem. 2008 May 16;283(20):13874-88. doi: 10.1074/jbc.M707820200. Epub 2008 Mar 13.

Abstract Both latent transforming growth factor-beta (TGF-beta)-binding proteins fibrillins are components of microfibril networks, and both interact with members of the TGF-beta family of...   Read More

  • Upcoming Events

    1. SFB Symposium: Highlights in skin research and beyond” Celebrating 12+ years of CRC 829 & Cologne Skin Research

      November 28 - November 30

    View All Events

© 2017 SFB 829

Durch die weitere Nutzung der Seite stimmst du der Verwendung von Cookies zu. Weitere Informationen

Die Cookie-Einstellungen auf dieser Website sind auf "Cookies zulassen" eingestellt, um das beste Surferlebnis zu ermöglichen. Wenn du diese Website ohne Änderung der Cookie-Einstellungen verwendest oder auf "Akzeptieren" klickst, erklärst du sich damit einverstanden.

Schließen