B2 WAGENER/ PAULSSON

Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures

B11 BAUMANN/SENGLEB2 WAGENER/ PAULSSONBechtel, M., Keller, M., Bloch, W., Sasaki, T., Boukamp, P., Zaucke, F., Paulsson, M., and Nischt, R., FASEB J. 2012 Sep;26(9):3637-48. doi: 10.1096/fj.11-194597. Epub 2012 May 23.

Abstract Nidogen-1 and nidogen-2 are homologous proteins found in all basement membranes (BMs). They show comparable binding activities in vitro and partially redundant functions...   Read More

Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure

B11 BAUMANN/SENGLEB2 WAGENER/ PAULSSONAgarwal, P., Zwolanek, D., Keene, D. R., Schulz, J.N., Blumbach, K., Heinegard, D., Zaucke, F., Paulsson, M., Krieg, T., Koch, M., and Eckes, B., J Biol Chem. 2012 Jun 29;287(27):22549-59. doi: 10.1074/jbc.M111.335935. Epub 2012 May 9.

Abstract The tensile and scaffolding properties of skin rely on the complex extracellular matrix (ECM) that surrounds cells, vasculature, nerves, and adnexus structures and...   Read More

Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells (2010)

B2 WAGENER/ PAULSSON Grimal, S., Puech, S., Wagener, R., Ventéo, S., Carroll, P., Fichard-Carroll A. 2010. Glia. 58, 1977-87.

Abstract: Growing evidence indicates that collagens perform crucial functions during the development and organization of the nervous system. Collagen XXVIII is a recently discovered...   Read More

Differential and restricted expression of novel collagen VI chains in mouse (2011)

B2 WAGENER/ PAULSSON Gara, S.K., Grumati, P., Squarzoni, S., Sabatelli, P., Urciuolo, A., Bonaldo, P., Paulsson, M., Wagener, R., Matrix Biol. 30, 248-57

Abstract: Recently, three novel collagen VI chains, α4, α5 and α6, were identified. These are thought to substitute for the collagen VI α3 chain,...   Read More

Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate ?-carboxylation (2011)

B2 WAGENER/ PAULSSON Neacsu, C.D., Grosch, M., Tejada, M., Winterpacht, A., Paulsson, M., Wagener, R., Tagariello, A. 2011. Matrix Biol. Aug 2011 [Epub ahead of print]

Abstract: UCMA (alternatively named GRP) is a novel member of the family of γ-carboxyglutamate (Gla) containing proteins that is mainly expressed in cartilage. We...   Read More

Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment (2009)

B2 WAGENER/ PAULSSON Gebauer JM, Keene DR, Olsen BR, Sorokin LM, Paulsson M, Wagener R. Matrix Biol. 2009 Oct;28(8):456-62.

Abstract The VWA domain-containing extracellular matrix protein AMACO has not been extensively characterized and its function remains unknown. It has been proposed as a...   Read More

The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene (2009)

B2 WAGENER/ PAULSSON Wagener R, Gara SK, Kobbe B, Paulsson M, Zaucke F. (2009) Matrix Biol. 2009 Jul;28(6):307-10.

Abstract In a recent study the DVWA gene located on human chromosome 3p24.3 was identified as a susceptibility locus for knee osteoarthritis in Japanese...   Read More

Expression of the collagen VI ?5 and ?6 chains in normal human skin and in skin of patients with collagen VI-related myopathies (2010)

B2 WAGENER/ PAULSSON Sabatelli P, Gara SK, Grumati P, Urciuolo A, Gualandi F, Curci R, Squarzoni S, Zamparelli A, Martoni E, Merlini L, Paulsson M, Bonaldo P, Wagener R (2010) J Invest Dermatol. 2011 Jan;131(1):99-107. Epub 2010 Sep 30.

Abstract Collagen VI is an extracellular matrix protein with critical roles in maintaining muscle and skin integrity and function. Skin abnormalities, including predisposition to...   Read More

Genetic analysis of fin development in zebrafish identifies Furin and Hemicentin1 as potential novel Fraser Syndrome disease genes

A9 HAMMERSCHMIDTB2 WAGENER/ PAULSSON Carney, T. J., Feitosa, N., Sonntag, C., Slanchev, K., Kluger, J., Kiyozumi, D., Gebauer, J., Coffin Talbot, J., Kimmel, C.B., Sekiguchi, K., Wagener, R., Schwarz, R., Ingham, P.I. and Hammerschmidt, M. PLoS Genet. 6, e1000907

Abstract Using forward genetics, we have identified the genes mutated in two classes of zebrafish fin mutants. The mutants of the first class are...   Read More

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