B4 ZIGRINO MAUCH

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T,...   Read More

Epidermal NLRP10 contributes to contact hypersensitivity responses in mice

Damm A, Giebeler N, Zamek J, Zigrino P, Kufer TA Eur. J. Immunol. 2016 May; PMID: 27221772 Abstract The NLR protein NLRP10 is highly...   Read More

Fibroblast-derived MMP-14 regulates collagen homeostasis in adult skin

Zigrino P, Brinckmann J, Niehoff A, Lu Y, Giebeler N, Eckes B, Kadler KE, Mauch C J. Invest. Dermatol. 2016 Apr; PMID: 27066886 Abstract...   Read More

The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV

Heuser S, Hufbauer M, Steiger J, Marshall J, Sterner-Kock A, Mauch C, Zigrino P, Akgül B Oncogene 2016 Jan; PMID: 26804167 Abstract Organ-transplant-recipients exhibit...   Read More

Matrix metalloproteinase 14 is required for fibrous tissue expansion

B4 ZIGRINO MAUCHTaylor SH, Yeung CY, Kalson NS, Lu Y, Zigrino P, Starborg T, Warwood S, Holmes DF, Canty-Laird EG, Mauch C, Kadler KE; Elife. 2015 Sep 21;4. pii: e09345. doi: 10.7554/eLife.09345.

Abstract Type I collagen-containing fibrils are major structural components of the extracellular matrix of vertebrate tissues, especially tendon, but how they are formed is...   Read More

Correlation of Merkel cell polyomavirus positivity with PDGFR? mutations and survivin expression in Merkel cell carcinoma

B4 ZIGRINO MAUCHBatinica M, Akgül B, Silling S, Mauch C, Zigrino P; J Dermatol Sci. 2015 Jul;79(1):43-9. doi: 10.1016/j.jdermsci.2015.04.002. Epub 2015 Apr 14.

Abstract BACKGROUND: Merkel cell carcinoma (MCC) is a neuroendocrine cancer of the skin postulated to originate through Merkel cell polyomavirus (MCPyV) oncogenesis and/or by...   Read More

Monocyte/macrophage MMP-14 modulates cell infiltration and T-cell attraction in contact dermatitis but not in murine wound healing

B4 ZIGRINO MAUCH Klose A, Zigrino P, Mauch C; Am J Pathol. 2013 Mar;182(3):755-64. doi: 10.1016/j.ajpath.2012.11.028.

Abstract   Monocyte infiltration and subsequent differentiation into macrophages has been shown to be crucial during inflammation. Metalloproteinases are key enzymes in these processes,...   Read More

PECAM1(+)/Sca1(+)/CD38(+) vascular cells transform into myofibroblast-like cells in skin wound repair

B2 WAGENER/ PAULSSONB4 ZIGRINO MAUCH Etich J, Bergmeier V, Frie C, Kreft S, Bengestrate L, Eming S, Mauch C, Eckes B, Ulus H, Lund FE, Rappl G, Abken H, Paulsson M, Brachvogel B; PLoS One. 2013;8(1):e53262. doi: 10.1371/journal.pone.0053262. Epub 2013 Jan 4.

Abstract   Skin injury induces the formation of new blood vessels by activating the vasculature in order to restore tissue homeostasis. Vascular cells may...   Read More

Loss of epidermal MMP-14 expression interferes with angiogenesis but not with re-epithelialization

B4 ZIGRINO MAUCHZigrino, P., Ayachi, O., Schild, A., Zamek, J., Kaltenberg, J., Nischt, R., Koch, M., and Mauch, C., Eur J Cell Biol. 2012 Oct;91(10):748-56. doi: 10.1016/j.ejcb.2012.05.003. Epub 2012 Jun 18.

Abstract Synthesis and activation of matrix metalloproteinases during wound healing are important for remodeling the extracellular matrix and modulating various cellular functions. The membrane-type...   Read More

Role of ADAM-15 in wound healing and melanoma development

B4 ZIGRINO MAUCHSchönefuß, A., Abety, A.N., Zamek, J., Mauch, C. and Zigrino, P., Exp Dermatol. 2012 Jun;21(6):437-42. doi: 10.1111/j.1600-0625.2012.01490.x.

Abstract Proteins of the a disintegrin and metalloprotease (ADAM) family are transmembrane proteins involved in ectodomain shedding and in cellular interactions. In skin, ADAM-15...   Read More

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