B4 ZIGRINO MAUCH

Migration of epithelial cells on laminins: RhoA antagonizes directionally persistent migration (2011)

B4 ZIGRINO MAUCH Zhang Z, Chometon G, Wen T, Qu H, Mauch C, Krieg T, Aumailley M. Eur J Cell Biol. Jan;90(1):1-12, 2011.

Abstract Spatial and temporal expression of laminin isoforms is assumed to provide specific local information to neighboring cells. Here, we report the remarkably selective...   Read More

MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development (2011)

B4 ZIGRINO MAUCH Jin G, Zhang F, Chan KM, Xavier Wong HL, Liu B, Cheah KS, Liu X, Mauch C, Liu D, Zhou Z. EMBO J. 2011 Jun 1;30(11):2281-93.

Abstract Notch signalling controls the differentiation of haematopoietic progenitor cells (HPCs). Here, we show that loss of membrane-type 1 matrix metalloproteinase (MT1-MMP, MMP14), a...   Read More

Accelerated wound repair in ADAM-9 knockout animals (2010)

B4 ZIGRINO MAUCH Mauch C, Zamek J, Abety AN, Grimberg G, Fox JW, Zigrino P. J Invest Dermatol 130(8): 2120-2130

Abstract ADAM-9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases (ADAMs) involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. Although the functions...   Read More

Stromal expression of MMP-13 is required for melanoma invasion and metastasis (2009)

B4 ZIGRINO MAUCH Zigrino P, Kuhn I, Bäuerle T, Zamek J, Fox JW, Neumann S, Licht A, Schorpp-Kistner M, Angel P, Mauch C. J Invest Dermatol 129(11):2686-93

Abstract Tumor invasion and metastasis of malignant melanoma have been shown to require proteolytic degradation of the extracellular environment achieved primarily by enzymes of...   Read More

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice (2009)

B4 ZIGRINO MAUCH Koegel H, von Tobel L, Schäfer M, Alberti S, Kremmer E, Mauch C, Hohl D, Wang XJ, Beer HD, Bloch W, Nordheim A, Werner S. J Clin Invest. Apr;119(4):899-910, 2009.

Abstract The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin...   Read More

A comparative study of empathy. The effects of psychiatric training

Khajavi F, Hekmat H Arch. Gen. Psychiatry 1971 Dec;25(6):490-3 PMID: 5141367 Abstract

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