Inflammation and metabolism in tissue repair and regeneration

Eming SA, Wynn TA, Martin P Science 2017 06;356(6342):1026-1030 PMID: 28596335 Abstract Tissue repair after injury is a complex, metabolically demanding process. Depending on...   Read More

Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice

Lucas T, Schäfer F, Müller P, Eming SA, Heckel A, Dimmeler S Nat Commun 2017 May;8:15162 PMID: 28462946 Abstract MicroRNAs (miRs) are small non-coding...   Read More

Keim oder kein Keim: Herausforderungen bei der Diagnose mykobakterieller Infektionen der Haut

Peters F, Batinica M, Plum G, Eming SA, Fabri M J Dtsch Dermatol Ges 2016 Dec;14(12):1227-1236 PMID: 27992147 Abstract Kutane Mykobakteriosen sind in Deutschland...   Read More

Bug or no bug: challenges in diagnosing cutaneous mycobacterial infections

Peters F, Batinica M, Plum G, Eming SA, Fabri M J Dtsch Dermatol Ges 2016 Dec;14(12):1227-1235 PMID: 27444929 Abstract Cutaneous mycobacterioses are rare in...   Read More

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

Ding X, Bloch W, Iden S, Rüegg MA, Hall MN, Leptin M, Partridge L, Eming SA Nat Commun 2016 Oct;7:13226 PMID: 27807348 Abstract Mammalian...   Read More

Tissue fibrosis: a pathomechanistically unresolved challenge and scary clinical problem

Eckes B, Eming SA Exp. Dermatol. 2016 Aug; PMID: 27513440 Abstract Fibrosis is defined as the replacement of healthy tissue by an excessive deposition...   Read More

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity

Jais A, Solas M, Backes H, Chaurasia B, Kleinridders A, Theurich S, Mauer J, Steculorum SM, Hampel B, Goldau J, Alber J, Förster CY,...   Read More

Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation

A5 BRÜNING/NIESSENB7 EMINGpublicationsKnuever J, Willenborg S, Ding X, Akyüz MD, Partridge L, Niessen CM, Brüning JC, Eming SA; J Immunol. 2015 Dec 1;195(11):5296-308. doi: 10.4049/jimmunol.1501237. Epub 2015 Oct 30.

Abstract Myeloid cells are key regulators of tissue homeostasis and disease. Alterations in cell-autonomous insulin/IGF-1 signaling in myeloid cells have recently been implicated in...   Read More

IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via Macrophages

B7 EMINGpublicationsHos D, Bucher F, Regenfuss B, Dreisow ML, Bock F, Heindl LM, Eming SA, Cursiefen C; Am J Pathol. 2015 Nov 19. pii: S0002-9440(15)00574-X. doi: 10.1016/j.ajpath.2015.09.012. [Epub ahead of print]

Abstract The role of IL-10, a primarily anti-inflammatory cytokine, in the regulation of inflammatory lymphangiogenesis is undetermined. Herein, we show that IL-10 modulates corneal...   Read More

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

B7 EMINGpublicationsFreudenberg U, Zieris A, Chwalek K, Tsurkan MV, Maitz MF, Atallah P, Levental KR, Eming SA, Werner C; J Control Release. 2015 Oct 22;220(Pt A):79-88. doi: 10.1016/j.jconrel.2015.10.028. [Epub ahead of print]


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