B7 EMING

Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis

B7 EMINGpublicationsWillenborg S, Eckes B, Brinckmann J, Krieg T, Waisman A, Hartmann K, Roers A, Eming SA; J Invest Dermatol. 2014 Jul;134(7):2005-15. doi: 10.1038/jid.2014.12. Epub 2014 Jan 9.

Abstract Conclusive evidence for the impact of mast cells (MCs) in skin repair is still lacking. Studies in mice examining the role of MC...   Read More

Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing

Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M,...   Read More

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

Deppermann C, Cherpokova D, Nurden P, Schulz JN, Thielmann I, Kraft P, Vögtle T, Kleinschnitz C, Dütting S, Krohne G, Eming SA, Nurden AT,...   Read More

Adult zebrafish as a model system for cutaneous wound-healing research

A9 HAMMERSCHMIDTB7 EMINGpublicationsRichardson R, Slanchev K, Kraus C, Knyphausen P, Eming S, Hammerschmidt M; J Invest Dermatol. 2013 Jun;133(6):1655-65. doi: 10.1038/jid.2013.16. Epub 2013 Jan 16.

Abstract Upon injury, the skin must quickly regenerate to regain its barrier function. In mammals, wound healing is rapid and scar free during embryogenesis,...   Read More

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming...   Read More

Extracellular matrix in angiogenesis: dynamic structures with translational potential (2011)

B7 EMINGpublications Eming SA, Hubbell JA, Exp Dermatol 20(7):605-1.

Abstract: The vascular network is an integral component of most organs. Beyond assuring an adequate supply of oxygen and nutrients for normal tissue function,...   Read More

A pivotal role for ? -1-antichymotrypsin in skin repair (2011)

B7 EMINGpublications Hoffmann DC, Textoris C, Oehme F, Klaassen T, Goppelt A, Römer A, Fugmann B, Davidson JM, Werner S. Krieg T, Eming SA. J Biol Chem

Abstract α1-antichymotrypsin (α1-ACT) is a specific inhibitor of leukocyte-derived chymotrypsin-like proteases with largely unknown functions in tissue repair. By examining human and murine skin...   Read More

Differential roles of macrophages in diverse phases of skin repair (2010)

B7 EMINGpublications Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA. J Immunol 2010

Abstract Influx of macrophages plays a crucial role in tissue repair. However, the precise function of macrophages during the healing response has remained a...   Read More

Alternative proteolytic processing of hepatocyte growth factor during wound repair

A3 NIEMANNB7 EMINGpublications Buchstein N, Hoffmann N, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA. Am J Pathol 174(6):2116-28.

Abstract Wound healing is a crucial regenerative process in all organisms. We examined expression, integrity, and function of the proteins in the hepatocyte growth...   Read More

Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds

B7 EMINGpublications Eming SA, Koch M, Krieger A, Brachvogel B, Kreft S, Bruckner-Tuderman L, Krieg T, Shannon JD, Fox JW. J Proteome Res. 2010 Sep 3;9(9):4758-66.

Abstract Chronic wounds associated with vascular disease, diabetes mellitus, or aging are leading causes of morbidity in western countries and represent an unresolved clinical...   Read More

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