A pivotal role for ? -1-antichymotrypsin in skin repair (2011)

B7 EMINGpublications Hoffmann DC, Textoris C, Oehme F, Klaassen T, Goppelt A, Römer A, Fugmann B, Davidson JM, Werner S. Krieg T, Eming SA. J Biol Chem

Abstract α1-antichymotrypsin (α1-ACT) is a specific inhibitor of leukocyte-derived chymotrypsin-like proteases with largely unknown functions in tissue repair. By examining human and murine skin...   Read More

Differential roles of macrophages in diverse phases of skin repair (2010)

B7 EMINGpublications Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA. J Immunol 2010

Abstract Influx of macrophages plays a crucial role in tissue repair. However, the precise function of macrophages during the healing response has remained a...   Read More

Alternative proteolytic processing of hepatocyte growth factor during wound repair

A3 NIEMANNB7 EMINGpublications Buchstein N, Hoffmann N, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA. Am J Pathol 174(6):2116-28.

Abstract Wound healing is a crucial regenerative process in all organisms. We examined expression, integrity, and function of the proteins in the hepatocyte growth...   Read More

Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds

B7 EMINGpublications Eming SA, Koch M, Krieger A, Brachvogel B, Kreft S, Bruckner-Tuderman L, Krieg T, Shannon JD, Fox JW. J Proteome Res. 2010 Sep 3;9(9):4758-66.

Abstract Chronic wounds associated with vascular disease, diabetes mellitus, or aging are leading causes of morbidity in western countries and represent an unresolved clinical...   Read More

Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope

B7 EMINGpublications Neumann S, Schneider M, Daugherty RL, Gottardi CJ, Eming SA, Beijer A, Noegel AA, Karakesisoglou I, J Biol Chem. 2010 Nov 5;285(45):34932-8.

Abstract: Nesprins and emerin are structural nuclear envelope proteins that tether nuclei to the cytoskeleton. In this work, we identified the cytoskeleton-associated α-N/E-catenins as...   Read More

Interrelation of immunity and tissue repair or regeneration

A9 HAMMERSCHMIDTB7 EMINGpublications Eming SA, Hammerschmidt M, Krieg T, Roers A. Semin Cell Dev Biol. 2009 Jul;20(5):517-27.

Abstract Although tremendous progress has been achieved in understanding the molecular basis of tissue repair and regeneration in diverse model organisms, the tendency of...   Read More

  • Upcoming Events

    1. SFB 829 Connector Meeting

      April 6 @ 3:00 pm - 5:30 pm
    2. International Investigative Dermatology 2018

      Mai 16 - Mai 18
    3. Women in Science and Society with Sarah Millar

      Juni 19 @ 1:30 pm - 6:00 pm
    4. SFB 829 Connector Meeting

      August 31 @ 3:00 pm - 5:30 pm
    5. International Symposium „Molecular Mechanisms regulating Skin Homeostasis“

      November 12 - November 14

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