B7 EMING

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

B7 EMINGFreudenberg U, Zieris A, Chwalek K, Tsurkan MV, Maitz MF, Atallah P, Levental KR, Eming SA, Werner C; J Control Release. 2015 Oct 22;220(Pt A):79-88. doi: 10.1016/j.jconrel.2015.10.028. [Epub ahead of print]

Pubmed

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

B2 WAGENER/ PAULSSONB3 ECKES KRIEGB7 EMINGKnipper JA, Willenborg S, Brinckmann J, Bloch W, Maaß T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R, Hammerschmidt M, Allen JE, Eming SA; Immunity. 2015 Oct 20;43(4):803-16. doi: 10.1016/j.immuni.2015.09.005.

Abstract Activation of the immune response during injury is a critical early event that determines whether the outcome of tissue restoration is regeneration or...   Read More

Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8

B7 EMINGpublicationsDing X, Lucas T, Marcuzzi GP, Pfister H, Eming SA; Cancer Res. 2015 Jan 15;75(2):330-43. doi: 10.1158/0008-5472.CAN-13-3007. Epub 2014 Nov 20.

Abstract Beta human papillomaviruses (HPV) have been suspected to be carcinogenic in nonmelanoma skin cancers (NMSC), but the basis for potential viral contributions to...   Read More

Wound repair and regeneration: mechanisms, signaling, and translation

B7 EMINGEming SA, Martin P, Tomic-Canic M; Sci Transl Med. 2014 Dec 3;6(265):265sr6. doi: 10.1126/scitranslmed.3009337.

Abstract The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are still poorly understood, and current therapies are limited. Poor...   Read More

Col6a1 null mice as a model to study skin phenotypes in patients with collagen VI related myopathies: expression of classical and novel collagen VI variants during wound healing

B2 WAGENER/ PAULSSONB7 EMINGLettmann S, Bloch W, Maaß T, Niehoff A, Schulz JN, Eckes B, Eming SA, Bonaldo P, Paulsson M, Wagener R; PLoS One. 2014 Aug 26;9(8):e105686. doi: 10.1371/journal.pone.0105686. eCollection 2014.

Abstract Patients suffering from collagen VI related myopathies caused by mutations in COL6A1, COL6A2 and COL6A3 often also display skin abnormalities, like formation of...   Read More

Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis

B7 EMINGWillenborg S, Eckes B, Brinckmann J, Krieg T, Waisman A, Hartmann K, Roers A, Eming SA; J Invest Dermatol. 2014 Jul;134(7):2005-15. doi: 10.1038/jid.2014.12. Epub 2014 Jan 9.

Abstract Conclusive evidence for the impact of mast cells (MCs) in skin repair is still lacking. Studies in mice examining the role of MC...   Read More

Embelin inhibits endothelial mitochondrial respiration and impairs neoangiogenesis during tumor growth and wound healing

Coutelle O, Hornig-Do HT, Witt A, Andree M, Schiffmann LM, Piekarek M, Brinkmann K, Seeger JM, Liwschitz M, Miwa S, Hallek M, Krönke M,...   Read More

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

Deppermann C, Cherpokova D, Nurden P, Schulz JN, Thielmann I, Kraft P, Vögtle T, Kleinschnitz C, Dütting S, Krohne G, Eming SA, Nurden AT,...   Read More

Adult zebrafish as a model system for cutaneous wound-healing research

A9 HAMMERSCHMIDTB7 EMINGRichardson R, Slanchev K, Kraus C, Knyphausen P, Eming S, Hammerschmidt M; J Invest Dermatol. 2013 Jun;133(6):1655-65. doi: 10.1038/jid.2013.16. Epub 2013 Jan 16.

Abstract Upon injury, the skin must quickly regenerate to regain its barrier function. In mammals, wound healing is rapid and scar free during embryogenesis,...   Read More

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming...   Read More

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