Extracellular matrix in angiogenesis: dynamic structures with translational potential (2011)

August 24, 2011B7 EMING Eming SA, Hubbell JA, Exp Dermatol 20(7):605-1.

Abstract: The vascular network is an integral component of most organs. Beyond assuring an adequate supply of oxygen and nutrients for normal tissue function,... Read More

A pivotal role for ? -1-antichymotrypsin in skin repair (2011)

August 15, 2011B7 EMING Hoffmann DC, Textoris C, Oehme F, Klaassen T, Goppelt A, Römer A, Fugmann B, Davidson JM, Werner S. Krieg T, Eming SA. J Biol Chem

Abstract α1-antichymotrypsin (α1-ACT) is a specific inhibitor of leukocyte-derived chymotrypsin-like proteases with largely unknown functions in tissue repair. By examining human and murine skin... Read More

Differential roles of macrophages in diverse phases of skin repair (2010)

August 3, 2011B7 EMING Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA. J Immunol 2010

Abstract Influx of macrophages plays a crucial role in tissue repair. However, the precise function of macrophages during the healing response has remained a... Read More

Alternative proteolytic processing of hepatocyte growth factor during wound repair

August 3, 2011A3 NIEMANN B7 EMING Buchstein N, Hoffmann N, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA. Am J Pathol 174(6):2116-28.

Abstract Wound healing is a crucial regenerative process in all organisms. We examined expression, integrity, and function of the proteins in the hepatocyte growth... Read More

Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds

August 3, 2011B7 EMING Eming SA, Koch M, Krieger A, Brachvogel B, Kreft S, Bruckner-Tuderman L, Krieg T, Shannon JD, Fox JW. J Proteome Res. 2010 Sep 3;9(9):4758-66.

Abstract Chronic wounds associated with vascular disease, diabetes mellitus, or aging are leading causes of morbidity in western countries and represent an unresolved clinical... Read More

Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope

November 5, 2010B7 EMING Neumann S, Schneider M, Daugherty RL, Gottardi CJ, Eming SA, Beijer A, Noegel AA, Karakesisoglou I, J Biol Chem. 2010 Nov 5;285(45):34932-8.

Abstract: Nesprins and emerin are structural nuclear envelope proteins that tether nuclei to the cytoskeleton. In this work, we identified the cytoskeleton-associated α-N/E-catenins as... Read More

Interrelation of immunity and tissue repair or regeneration

July 8, 2009A9 HAMMERSCHMIDT B7 EMING Eming SA, Hammerschmidt M, Krieg T, Roers A. Semin Cell Dev Biol. 2009 Jul;20(5):517-27.

Abstract Although tremendous progress has been achieved in understanding the molecular basis of tissue repair and regeneration in diverse model organisms, the tendency of... Read More

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