publications

Longevity through DNA damage tolerance

A7 SCHUMACHERCastells-Roca L, Mueller MM, Schumacher B; Cell Cycle. 2015;14(4):467-8. doi: 10.1080/15384101.2015.1006543.

Pubmed

Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation

A5 BRÜNING/NIESSENB7 EMINGKnuever J, Willenborg S, Ding X, Akyüz MD, Partridge L, Niessen CM, Brüning JC, Eming SA; J Immunol. 2015 Dec 1;195(11):5296-308. doi: 10.4049/jimmunol.1501237. Epub 2015 Oct 30.

Abstract Myeloid cells are key regulators of tissue homeostasis and disease. Alterations in cell-autonomous insulin/IGF-1 signaling in myeloid cells have recently been implicated in...   Read More

IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via Macrophages

B7 EMINGHos D, Bucher F, Regenfuss B, Dreisow ML, Bock F, Heindl LM, Eming SA, Cursiefen C; Am J Pathol. 2015 Nov 19. pii: S0002-9440(15)00574-X. doi: 10.1016/j.ajpath.2015.09.012. [Epub ahead of print]

Abstract The role of IL-10, a primarily anti-inflammatory cytokine, in the regulation of inflammatory lymphangiogenesis is undetermined. Herein, we show that IL-10 modulates corneal...   Read More

Invasion of Herpes Simplex Virus Type 1 into Murine Epidermis: An Ex Vivo Infection Study

Rahn E, Petermann P, Thier K, Bloch W, Morgner J, Wickström SA, Knebel-Mörsdorf D J. Invest. Dermatol. 2015 Dec;135(12):3009-16 PMID: 26203638 Abstract Herpes simplex...   Read More

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P,...   Read More

The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity

Troilo H, Barrett AL, Wohl AP, Jowitt TA, Collins RF, Bayley CP, Zuk AV, Sengle G, Baldock C Biochem. Soc. Trans. 2015 Oct;43(5):795-800 PMID:...   Read More

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

B7 EMINGFreudenberg U, Zieris A, Chwalek K, Tsurkan MV, Maitz MF, Atallah P, Levental KR, Eming SA, Werner C; J Control Release. 2015 Oct 22;220(Pt A):79-88. doi: 10.1016/j.jconrel.2015.10.028. [Epub ahead of print]

Pubmed

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

Knipper JA, Willenborg S, Brinckmann J, Bloch W, Maaß T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R,...   Read More

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

B2 WAGENER/ PAULSSONB3 ECKES KRIEGB7 EMINGKnipper JA, Willenborg S, Brinckmann J, Bloch W, Maaß T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R, Hammerschmidt M, Allen JE, Eming SA; Immunity. 2015 Oct 20;43(4):803-16. doi: 10.1016/j.immuni.2015.09.005.

Abstract Activation of the immune response during injury is a critical early event that determines whether the outcome of tissue restoration is regeneration or...   Read More

The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?

Sengle G, Sakai LY Matrix Biol. 2015 Sep;47:3-12 PMID: 25957947 Abstract The fibrillins, large extracellular matrix molecules, are polymerized to form “microfibrils.” The fibrillin...   Read More

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