ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING

Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A,...   Read More

Connecting immune deficiency and inflammation

Pasparakis M, Kelliher M Science 2018 08;361(6404):756-757 PMID: 30139862 Abstract

B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice

Knittel G, Liedgens P, Korovkina D, Seeger JM, Al-Baldawi Y, Al-Maarri M, Fritz C, Vlantis K, Bezhanova S, Scheel AH, Wolz OO, Reimann M,...   Read More

Opposing role of tumor necrosis factor receptor 1 signaling in T cell-mediated hepatitis and bacterial infection in mice

Wroblewski R, Armaka M, Kondylis V, Pasparakis M, Walczak H, Mittrücker HW, Schramm C, Lohse AW, Kollias G, Ehlken H Hepatology 2016 08;64(2):508-21 PMID:...   Read More

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis

Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR Eur. Respir....   Read More

Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes

Aatsinki SM, Elkhwanky MS, Kummu O, Karpale M, Buler M, Viitala P, Rinne V, Mutikainen M, Tavi P, Franko A, Wiesner RJ, Chambers KT,...   Read More

Leucurogin and melanoma therapy

Almeida MC, Santos IC, Paschoalin T, Travassos LR, Mauch C, Zigrino P, Pesquero JB, Pesquero JL, Higuchi DA Toxicon 2019 Mar;159:22-31 PMID: 30611825 Abstract...   Read More

Epithelial polarity limits EMT

Persa OD, Niessen CM Nat. Cell Biol. 2019 Mar;21(3):299-300 PMID: 30824839 Abstract Epithelial–mesenchymal transition (EMT) is crucial for development, and for dissemination and invasion...   Read More

The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival

Ayachi O, Barlin M, Broxtermann PN, Kashkar H, Mauch C, Zigrino P Cell Oncol (Dordr) 2019 Feb; PMID: 30778852 Abstract BACKGROUND: The X-linked inhibitor...   Read More

Augmented contractility of murine femoral arteries in a streptozotocin diabetes model is related to increased phosphorylation of MYPT1

Lubomirov LT, Gagov H, Schroeter MM, Wiesner RJ, Franko A Physiol Rep 2019 Feb;7(3):e13975 PMID: 30740930 Abstract Diabetes mellitus (DM) is a metabolic disorder...   Read More

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