publications

Centrioles in the mouse: cilia and beyond

Bazzi H, Anderson KV Cell Cycle 2014;13(18):2809 PMID: 25486466 Abstract

Wound repair and regeneration: mechanisms, signaling, and translation

B7 EMINGEming SA, Martin P, Tomic-Canic M; Sci Transl Med. 2014 Dec 3;6(265):265sr6. doi: 10.1126/scitranslmed.3009337.

Abstract The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are still poorly understood, and current therapies are limited. Poor...   Read More

Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

A4 PASPARAKISKumari S, Redouane Y, Lopez-Mosqueda J, Shiraishi R, Romanowska M, Lutzmayer S, Kuiper J, Martinez C, Dikic I, Pasparakis M, Ikeda F; Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03422.

Abstract Linear Ubiquitin chain Assembly Complex (LUBAC) is an E3 ligase complex that generates linear ubiquitin chains and is important for tumour necrosis factor...   Read More

The respiratory chain supercomplex organization is independent of COX7a2l isoforms

publicationsMourier A, Matic S, Ruzzenente B, Larsson NG, Milenkovic D; Cell Metab. 2014 Dec 2;20(6):1069-75. doi: 10.1016/j.cmet.2014.11.005.

Abstract The organization of individual respiratory chain complexes into supercomplexes or respirasomes has attracted great interest because of the implications for cellular energy conversion....   Read More

Mammalian aPKC/Par polarity complex mediated regulation of epithelial division orientation and cell fate

Vorhagen S, Niessen CM Exp. Cell Res. 2014 Nov;328(2):296-302 PMID: 25128813 Abstract Oriented cell division is a key regulator of tissue architecture and crucial...   Read More

Epidermal polarity genes in health and disease

Tellkamp F, Vorhagen S, Niessen CM Cold Spring Harb Perspect Med 2014 Dec;4(12):a015255 PMID: 25452423 Abstract The epidermis of the skin is a highly...   Read More

Epidermal Polarity Genes in Health and Disease

A5 BRÜNING/NIESSENTellkamp F, Vorhagen S, Niessen CM; Cold Spring Harb Perspect Med. 2014 Dec 1;4(12):a015255. doi: 10.1101/cshperspect.a015255.

Abstract The epidermis of the skin is a highly polarized, metabolic tissue with important innate immune functions. The polarity of the epidermis is, for...   Read More

Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation

publicationsBaggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG; Nucleic Acids Res. 2014 Dec 16;42(22):13920-38. doi: 10.1093/nar/gku1132. Epub 2014 Nov 26.

Abstract Members of the pentatricopeptide repeat domain (PPR) protein family bind RNA and are important for post-transcriptional control of organelle gene expression in unicellular...   Read More

DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage

A7 SCHUMACHERMueller MM, Castells-Roca L, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JI, Benzing T, Schermer B, Schumacher B; Nat Cell Biol. 2014 Dec;16(12):1168-79. doi: 10.1038/ncb3071. Epub 2014 Nov 24.

Abstract Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility and premature ageing. It remains poorly understood how DNA damage...   Read More

A C. elegans homolog of the Cockayne syndrome complementation group A gene

A7 SCHUMACHERBabu V, Hofmann K, Schumacher B; DNA Repair (Amst). 2014 Dec;24:57-62. doi: 10.1016/j.dnarep.2014.09.011. Epub 2014 Nov 8.

Abstract Cockayne syndrome (CS) is a debilitating and complex disorder that results from inherited mutations in the CS complementation genes A and B, CSA...   Read More

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