Abstract Conclusive evidence for the impact of mast cells (MCs) in skin repair is still lacking. Studies in mice examining the role of MC... Read More
Eckes B, Krieg T, Wickström SA Exp. Dermatol. 2014 Jul;23(7):453-6 PMID: 24773528 Abstract Cell-matrix adhesions provide structural stability to the tissue and regulate intracellular... Read More
Kim C, Pasparakis M EMBO Mol Med 2014 Jul;6(7):970-83 PMID: 24952939 Abstract The nuclear factor kappa B (NF-κB) signalling pathway exhibits both tumour-promoting and... Read More
Marteijn JA, Lans H, Vermeulen W, Hoeijmakers JH Nat. Rev. Mol. Cell Biol. 2014 Jul;15(7):465-81 PMID: 24954209 Abstract Nucleotide excision repair (NER) eliminates various... Read More
Abstract Strong inhibition of NF-κB signaling in the epidermis results in spontaneous skin inflammation in mice and men. As there is evidence for... Read More
Abstract Skin fibrosis is characterized by activated fibroblasts and an altered architecture of the extracellular matrix. Excessive deposition of extracellular matrix proteins and... Read More
Abstract Collagen VI-related myopathies are disorders of connective tissue presenting with an overlap phenotype combining clinical involvement from the muscle and from the... Read More
Abstract The epidermal growth factor receptor (EGFR) system is a key regulator of epithelial development and homeostasis. Its functions in the sebaceous gland (SG),... Read More
Abstract Collagen XXII, a FACIT (fibril-associated collagen with interrupted triple helices), is expressed at the myotendinous junction and the articular surface of joint... Read More
Abstract Intermittent intense ultraviolet (UV) exposure represents an important aetiological factor in the development of malignant melanoma. The ability of UV radiation to... Read More
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