Basement membranes in skin: unique matrix structures with diverse functions? (2009)

publications Breitkreutz D, Mirancea N, Nischt R. Histochem Cell Biol. 2009 Jul;132(1):1-10.

Abstract The view of extracellular matrix (ECM) has evolved from a merely scaffolding and space filling tissue element to an interface actively controlling cellular...   Read More

Basement membrane protein nidogen-1 shapes hippocampal synaptic plasticity and excitability (2010)

publications Vasudevan A, Ho MS, Weiergräber M, Nischt R, Schneider T, Lie A, Smyth N, Köhling R. Hippocampus. 2010 May;20(5):608-20.

Abstract The basement membrane (BM) is a specialized form of extracellular matrix (ECM) underlying epithelia and endothelia and surrounding many types of mesenchymal cells....   Read More

Transcription-blocking DNA damage in aging: a mechanism for hormesis (2009)

A7 SCHUMACHER Schumacher B. Bioessays. 2009 Dec;31(12):1347-56.

Abstract Recent evidence from studies on DNA repair systems that are implicated in accelerated aging syndromes, have revealed a mechanism through which low levels...   Read More

Transcription-blocking DNA damage in aging and longevity (2009)

A7 SCHUMACHER Garinis GA, Schumacher B. Cell Cycle. 2009 Jul 15;8(14):2134-5.


Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment (2009)

B2 WAGENER/ PAULSSON Gebauer JM, Keene DR, Olsen BR, Sorokin LM, Paulsson M, Wagener R. Matrix Biol. 2009 Oct;28(8):456-62.

Abstract The VWA domain-containing extracellular matrix protein AMACO has not been extensively characterized and its function remains unknown. It has been proposed as a...   Read More

Enhanced contact allergen and UVB induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1 (2010)

publications Hedrych- Ozimina A, Hao Z, Pofahl R, Ussath D, Knaup R, Behrendt K, Krieg T, Haase I. Cell Death and Differentiation (2010) Aug 6.

Abstract FAS/CD95/Apo-1 is a ubiquitously expressed cell-surface receptor involved in the initiation of programmed cell death. Its function in epidermal keratinocytes has been incompletely...   Read More

Differential roles of macrophages in diverse phases of skin repair (2010)

B7 EMING Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA. J Immunol 2010

Abstract Influx of macrophages plays a crucial role in tissue repair. However, the precise function of macrophages during the healing response has remained a...   Read More

Alternative proteolytic processing of hepatocyte growth factor during wound repair

A3 NIEMANNB7 EMING Buchstein N, Hoffmann N, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA. Am J Pathol 174(6):2116-28.

Abstract Wound healing is a crucial regenerative process in all organisms. We examined expression, integrity, and function of the proteins in the hepatocyte growth...   Read More

Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status (2010)

publications Belluoccio D, Etich J, Rosenbaum S, Frie C, Grskovic I, Stermann J, Ehlen H, Vogel S, Zaucke F, von der Mark K, Bateman JF, Brachvogel B. J Bone Miner Res. 2010 Jun;25(6):1267-81.

Abstract Axial growth of long bones occurs through a coordinated process of growth plate chondrocyte proliferation and differentiation. This maturation of chondrocytes is reflected...   Read More

Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds

B7 EMING Eming SA, Koch M, Krieger A, Brachvogel B, Kreft S, Bruckner-Tuderman L, Krieg T, Shannon JD, Fox JW. J Proteome Res. 2010 Sep 3;9(9):4758-66.

Abstract Chronic wounds associated with vascular disease, diabetes mellitus, or aging are leading causes of morbidity in western countries and represent an unresolved clinical...   Read More

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