publications

Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway

Troilo H, Barrett AL, Zuk AV, Lockhart-Cairns MP, Wohl AP, Bayley CP, Dajani R, Tunnicliffe RB, Green L, Jowitt TA, Sengle G, Baldock C...   Read More

The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV

Heuser S, Hufbauer M, Steiger J, Marshall J, Sterner-Kock A, Mauch C, Zigrino P, Akgül B Oncogene 2016 Jan; PMID: 26804167 Abstract Organ-transplant-recipients exhibit...   Read More

Systemic DNA damage responses in aging and diseases

Ribezzo F, Shiloh Y, Schumacher B Semin. Cancer Biol. 2016 Jan; PMID: 26773346 Abstract The genome is constantly attacked by a variety of genotoxic...   Read More

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation

Pilecki B, Holm AT, Schlosser A, Moeller JB, Wohl AP, Zuk AV, Heumüller SE, Wallis R, Moestrup SK, Sengle G, Holmskov U, Sorensen GL...   Read More

Foxd3 Promotes Exit from Naive Pluripotency through Enhancer Decommissioning and Inhibits Germline Specification

Respuela P, Nikolić M, Tan M, Frommolt P, Zhao Y, Wysocka J, Rada-Iglesias A Cell Stem Cell 2016 Jan;18(1):118-33 PMID: 26748758 Abstract Following implantation,...   Read More

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling

Giampietro C, Disanza A, Bravi L, Barrios-Rodiles M, Corada M, Frittoli E, Savorani C, Lampugnani MG, Boggetti B, Niessen C, Wrana JL, Scita G,...   Read More

Longevity through DNA damage tolerance

A7 SCHUMACHERpublicationsCastells-Roca L, Mueller MM, Schumacher B; Cell Cycle. 2015;14(4):467-8. doi: 10.1080/15384101.2015.1006543.

Pubmed

Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation

A5 BRÜNING/NIESSENB7 EMINGpublicationsKnuever J, Willenborg S, Ding X, Akyüz MD, Partridge L, Niessen CM, Brüning JC, Eming SA; J Immunol. 2015 Dec 1;195(11):5296-308. doi: 10.4049/jimmunol.1501237. Epub 2015 Oct 30.

Abstract Myeloid cells are key regulators of tissue homeostasis and disease. Alterations in cell-autonomous insulin/IGF-1 signaling in myeloid cells have recently been implicated in...   Read More

IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via Macrophages

B7 EMINGpublicationsHos D, Bucher F, Regenfuss B, Dreisow ML, Bock F, Heindl LM, Eming SA, Cursiefen C; Am J Pathol. 2015 Nov 19. pii: S0002-9440(15)00574-X. doi: 10.1016/j.ajpath.2015.09.012. [Epub ahead of print]

Abstract The role of IL-10, a primarily anti-inflammatory cytokine, in the regulation of inflammatory lymphangiogenesis is undetermined. Herein, we show that IL-10 modulates corneal...   Read More

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P,...   Read More

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