Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program

Do NN, Willenborg S, Eckes B, Jüngst C, Sengle G, Zaucke F, Eming SA J. Immunol. 2018 Jul;201(2):663-674 PMID: 29898959 Abstract Myeloid cells can...   Read More

E-cadherin binds to desmoglein to facilitate desmosome assembly

Shafraz O, Rübsam M, Stahley SN, Caldara AL, Kowalczyk AP, Niessen CM, Sivasankar S Elife 2018 07;7 PMID: 29999492 Abstract Desmosomes are adhesive junctions...   Read More

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas

Kunz M, Löffler-Wirth H, Dannemann M, Willscher E, Doose G, Kelso J, Kottek T, Nickel B, Hopp L, Landsberg J, Hoffmann S, Tüting T,...   Read More

Nuclear Genomic Instability and Aging

Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD Annu. Rev. Biochem. 2018 06;87:295-322 PMID: 29925262 Abstract The nuclear genome decays...   Read More

Cell adhesion and mechanics as drivers of tissue organization and differentiation: local cues for large scale organization

Wickström SA, Niessen CM Curr. Opin. Cell Biol. 2018 10;54:89-97 PMID: 29864721 Abstract Biological patterns emerge through specialization of genetically identical cells to take...   Read More

Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis

Vorhagen S, Kleefisch D, Persa OD, Graband A, Schwickert A, Saynisch M, Leitges M, Niessen CM, Iden S Oncogene 2018 09;37(37):5136-5146 PMID: 29789715 Abstract...   Read More

MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO

Bianco JN, Schumacher B Nucleic Acids Res. 2018 Jul;46(12):6129-6139 PMID: 29788264 Abstract Ultraviolet (UV) induces distorting lesions to the DNA that can lead to...   Read More

Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development

Pogoda HM, Riedl-Quinkertz I, Löhr H, Waxman JS, Dale RM, Topczewski J, Schulte-Merker S, Hammerschmidt M Development 2018 05;145(9) PMID: 29650589 Abstract Zebrafish mutants...   Read More

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer

Pichlo C, Toelzer C, Chojnacki K, Öcal S, Uthoff M, Ruegenberg S, Hermanns T, Schacherl M, Denzel MS, Hofmann K, Niefind K, Baumann U...   Read More

Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation

Fueyo R, Iacobucci S, Pappa S, Estarás C, Lois S, Vicioso-Mantis M, Navarro C, Cruz-Molina S, Reyes JC, Rada-Iglesias Á, de la Cruz X,...   Read More

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