publications

JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis

A10 IDENpublicationsTuncay H, Brinkmann BF, Steinbacher T, Schürmann A, Gerke V, Iden S, Ebnet K; Nat Commun. 2015 Aug 26;6:8128. doi: 10.1038/ncomms9128.

Abstract Planar spindle orientation in polarized epithelial cells depends on the precise localization of the dynein-dynactin motor protein complex at the lateral cortex. The...   Read More

Epithelial Cell Death and Inflammation in Skin

Kumari S, Pasparakis M Curr. Top. Microbiol. Immunol. 2015 Aug; PMID: 26275873 Abstract The presence of dying cells in inflamed tissues has been recognized...   Read More

Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms

A7 SCHUMACHERpublicationsEdifizi D, Schumacher B; Biomolecules. 2015 Aug 13;5(3):1855-69. doi: 10.3390/biom5031855.

Abstract DNA damage causally contributes to aging and cancer. Congenital defects in nucleotide excision repair (NER) lead to distinct cancer-prone and premature aging syndromes....   Read More

Comparing the Hem- and Lymphangiogenic Profile of Conjunctival and Uveal Melanoma Cell Lines

A10 IDENpublicationsRefaian N, Schlereth SL, Koch KR, Notara M, Hos D, Mescher M, Iden S, Bosch JJ, Jager MJ, Cursiefen C, Heindl LM; Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5691-7. doi: 10.1167/iovs.15-16829.

Abstract PURPOSE: Malignant melanomas of the ocular surface (conjunctival melanoma [CM]) and within the eye (uveal melanoma [UM]) show different types of metastatic behavior....   Read More

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

publicationsLagouge M, Mourier A, Lee HJ, Spåhr H, Wai T, Kukat C, Silva Ramos E, Motori E, Busch JD, Siira S; German Mouse Clinic Consortium, Kremmer E, Filipovska A, Larsson NG; PLoS Genet. 2015 Aug 6;11(8):e1005423. doi: 10.1371/journal.pgen.1005423. eCollection 2015.

Abstract We have studied the in vivo role of SLIRP in regulation of mitochondrial DNA (mtDNA) gene expression and show here that it stabilizes...   Read More

Structure, evolution and expression of collagen XXVIII: Lessons from the zebrafish

B2 WAGENER/ PAULSSONpublicationsGebauer JM, Kobbe B, Paulsson M, Wagener R; Matrix Biol. 2015 Jul 31. pii: S0945-053X(15)00124-9. doi: 10.1016/j.matbio.2015.07.001. [Epub ahead of print]

Abstract Collagen XXVIII is the last discovered member of the collagen superfamily and thus has been only sparsely investigated. We studied collagen XXVIII in...   Read More

Force generation and transmission in keloid fibroblasts: dissecting the role of mechanosensitive molecules in cell function

Schneider D, Wickström SA Exp. Dermatol. 2015 Aug;24(8):574-5 PMID: 25959359 Abstract

Correlation of Merkel cell polyomavirus positivity with PDGFR? mutations and survivin expression in Merkel cell carcinoma

B4 ZIGRINO MAUCHpublicationsBatinica M, Akgül B, Silling S, Mauch C, Zigrino P; J Dermatol Sci. 2015 Jul;79(1):43-9. doi: 10.1016/j.jdermsci.2015.04.002. Epub 2015 Apr 14.

Abstract BACKGROUND: Merkel cell carcinoma (MCC) is a neuroendocrine cancer of the skin postulated to originate through Merkel cell polyomavirus (MCPyV) oncogenesis and/or by...   Read More

Par Proteins in Tumor Formation and Progression

Mescher, M., and Iden, S. (2015). Cell Polarity 2. Role in Dev. and Dis. Springer 2, 344. Book chapter.

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Sengle G, Carlberg V, Tufa SF, Charbonneau NL, Smaldone S, Carlson EJ, Ramirez F, Keene DR, Sakai LY PLoS Genet. 2015 Jun;11(6):e1005340 PMID: 26114882...   Read More

© 2017 SFB 829