DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway

Mandemaker IK, van Cuijk L, Janssens RC, Lans H, Bezstarosti K, Hoeijmakers JH, Demmers JA, Vermeulen W, Marteijn JA Sci Rep 2017 Nov;7(1):15353 PMID:...   Read More

Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development

Vallecillo-García P, Orgeur M, Vom Hofe-Schneider S, Stumm J, Kappert V, Ibrahim DM, Börno ST, Hayashi S, Relaix F, Hildebrandt K, Sengle G, Koch...   Read More

Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation

Rada-Iglesias A Mol. Syst. Biol. 2017 10;13(10):950 PMID: 29061670 Abstract

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans

Wilson DM, Rieckher M, Williams AB, Schumacher B Nucleic Acids Res. 2017 Sep;45(16):9467-9480 PMID: 28934497 Abstract DNA interstrand crosslinks (ICLs) are generated by endogenous...   Read More

Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples

Rehimi R, Bartusel M, Solinas F, Altmüller J, Rada-Iglesias A J Vis Exp 2017 08;(126) PMID: 28872116 Abstract Chromatin immunoprecipitation (ChIP) is a widely-used...   Read More

Microstructure dependent binding of pigment epithelium derived factor (PEDF) to type I collagen fibrils

Cauble M, Yang P, Baumann U, Gebauer JM, Orr BG, Duong LT, Banaszak Holl MM J. Struct. Biol. 2017 Aug;199(2):132-139 PMID: 28602715 Abstract Pigment...   Read More

Dysfunction of the MDM2/p53 axis is linked to premature aging

Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah MK, Saha B, Hisama FM, Rading K, Goebel I, Schütz P, Speit G,...   Read More

Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans

Edifizi D, Nolte H, Babu V, Castells-Roca L, Mueller MM, Brodesser S, Krüger M, Schumacher B Cell Rep 2017 Aug;20(9):2026-2043 PMID: 28854356 Abstract DNA...   Read More

Pathophysiological Mechanisms in Sclerosing Skin Diseases

Eckes B, Wang F, Moinzadeh P, Hunzelmann N, Krieg T Front Med (Lausanne) 2017;4:120 PMID: 28868289 Abstract Sclerosing skin diseases represent a large number...   Read More

Treatment of Early Syphilis

Fätkenheuer G, Suarez I, Platten M, Fabri M, Lehmann C Clin. Infect. Dis. 2017 Oct;65(10):1767 PMID: 29091229 Abstract

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