B7 Eming

Abstract

Macrophages and polymorphonuclear leukocytes are key elements of the repair response following tissue injury. However, their role in skin repair and homeostasis is not well understood. The aim of the proposal is to unravel the impact of macrophage/neutrophil functions on the diverse phases of the healing response and the restauration of skin homeostasis. Furthermore, we will characterize origin and differentiation of macrophage subsets in wound tissue and investigate the differential contribution of these subsets to skin repair.

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