Monthly Archives: August 2009

Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice (2009)

B4 ZIGRINO MAUCH Koegel H, von Tobel L, Schäfer M, Alberti S, Kremmer E, Mauch C, Hohl D, Wang XJ, Beer HD, Bloch W, Nordheim A, Werner S. J Clin Invest. Apr;119(4):899-910, 2009.

Abstract The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin...   Read More

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity

B3 ECKES KRIEG Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV. Blood 114, 4897-906, 2009

Abstract Endorepellin, the C-terminal domain of perlecan, is a powerful angiogenesis inhibitor. To dissect the mechanism of endorepellin-mediated endothelial silencing, we used an antibody...   Read More

The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development

A9 HAMMERSCHMIDT Slanchev K., Carney, T. J., Stemmler, M. P., Koschorz, M., Amsterdam, A., Schwarz, H. and Hammerschmidt, M. PLoS Genet. 5, e1000563

Abstract The aberrant expression of the transmembrane protein EpCAM is associated with tumor progression, affecting different cellular processes such as cell-cell adhesion, migration, proliferation,...   Read More

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