parvin complex: the kinase is dead, long live the pseudokinase!

January 20, 2010A11 WICKSTRÖMWickström, S.A., Lange, A., Montanez, E., and Fässler, R., EMBO J. 2010 Jan 20;29(2):281-91. doi: 10.1038/emboj.2009.376. Epub 2009 Dec 24.

Abstract Dynamic interactions of cells with their environment regulate multiple aspects of tissue morphogenesis and function. Integrins are the major class of cell... Read More

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

January 6, 2010A11 WICKSTRÖMWickström, S.A., Masoumi, K.C., Khochbin, S., Fässler, R., and Massoumi, R., EMBO J. 2010 Jan 6;29(1):131-44. doi: 10.1038/emboj.2009.317. Epub 2009 Nov 5.

Abstract CYLD is a tumour-suppressor gene that is mutated in a benign skin tumour syndrome called cylindromatosis. The CYLD gene product is a deubiquitinating... Read More

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Monthly Archives: January 2010

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

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