A function for Rac1 in the terminal differentiation and pigmentation of hair

January 24, 2012A3 NIEMANN A5 BRÜNING/NIESSEN Behrendt K, Klatte J, Pofahl R, Bloch W, Smyth N, Tscharntke M, Krieg T, Paus R, Niessen CM, Niemann C, Brakebusch C, Haase I; J Cell Sci. 2012 Feb 15;125(Pt 4):896-905. doi: 10.1242/jcs.091868. Epub 2012 Jan 24.

Abstract The small GTPase Rac1 is ubiquitously expressed in proliferating and differentiating layers of the epidermis and hair follicles. Previously, Rac1 was shown to... Read More

Microenvironmental regulation by fibrillin-1

January 13, 2012B12 SENGLESengle, G., Tsutsui, K., Keene, D.R., Tufa, S.F., Carlson, E.J., Charbonneau, N.L., Ono, R.N., Sasaki, T., Wirtz, M.K., Samples, J.R., Fessler, L.I., Fessler, J.H., Sekiguchi, K.,Hayflick, S.J., and Sakai, L.Y., PLoS Genet. 2012 Jan;8(1):e1002425. doi: 10.1371/journal.pgen.1002425. Epub 2012 Jan 5.

Abstract Fibrillin-1 is a ubiquitous extracellular matrix molecule that sequesters latent growth factor complexes. A role for fibrillin-1 in specifying tissue microenvironments has... Read More

Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation

January 6, 2012B14 DENZEL

Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS... Read More

The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network

January 1, 2012A10 IDENEllenbroek, S.I.J., Iden, S., Collard, J.G., Small GTPases. 2012 Jan-Mar;3(1):4-14. doi: 10.4161/sgtp.19379. Epub 2012 Jan 1

Abstract Polarized cell migration is a crucial process in the development and repair of tissues, as well as in pathological conditions, including cancer.... Read More

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Monthly Archives: January 2012