Monthly Archives: June 2012

Role of ADAM-15 in wound healing and melanoma development

B4 ZIGRINO MAUCHSchönefuß, A., Abety, A.N., Zamek, J., Mauch, C. and Zigrino, P., Exp Dermatol. 2012 Jun;21(6):437-42. doi: 10.1111/j.1600-0625.2012.01490.x.

Abstract Proteins of the a disintegrin and metalloprotease (ADAM) family are transmembrane proteins involved in ectodomain shedding and in cellular interactions. In skin, ADAM-15...   Read More

The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1

publicationsSeeger-Nukpezah, T., Liebau, M.C., Höpker, K., Lamkemeyer, T., Benzing, T., Golemis, E.A., Schermer, B., PLoS One. 2012;7(6):e38838. doi: 10.1371/journal.pone.0038838. Epub 2012 Jun 11.

Abstract Polo-like kinase (Plk1) plays a central role in regulating the cell cycle. Plk1-mediated phosphorylation is essential for centrosome maturation, and for numerous mitotic...   Read More

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

Schwertman P, Lagarou A, Dekkers DH, Raams A, van der Hoek AC, Laffeber C, Hoeijmakers JH, Demmers JA, Fousteri M, Vermeulen W, Marteijn JA...   Read More

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis

A10 IDEN Iden S., van Riel WE, Schäfer R, Song JY, Hirose T, Ohno S, Collard JG; Cancer Cell. 2012 Sep 11;22(3):389-403. doi: 10.1016/j.ccr.2012.08.004.

Abstract   Cell polarization is crucial during development and tissue homeostasis and is regulated by conserved proteins of the Scribble, Crumbs, and Par complexes....   Read More

Classical and desmosomal cadherins at a glance

A1 NIESSEN Saito M, Tucker DK, Kohlhorst D, Niessen CM, Kowalczyk AP, J Cell Sci. 2012 Jun 1;125(Pt 11):2547-52. doi: 10.1242/jcs.066654.

Pubmed

Adherens junctions in Mammalian development, homeostasis and disease: lessons from mice

A1 NIESSEN Boggetti B, Niessen CM, Subcell Biochem. 2012;60:321-55. doi: 10.1007/978-94-007-4186-7_14.

Abstract Mice have proven to be a particularly powerful model to study molecular mechanisms of development and disease. The reason for this is the...   Read More

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