Monthly Archives: May 2013

CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes

B13 FABRIKlug-Micu GM, Stenger S, Sommer A, Liu PT, Krutzik SR, Modlin RL, Fabri M; Immunology. 2013 May;139(1):121-8. doi: 10.1111/imm.12062.

Abstract The ability of T cells to activate antimicrobial pathways in infected macrophages is essential to host defence against many intracellular pathogens. Here, we...   Read More

mtDNA makes a U-turn for the mitochondrial nucleoid

publications Kukat C, Larsson NG; Trends Cell Biol. 2013 Sep;23(9):457-63. doi: 10.1016/j.tcb.2013.04.009. Epub 2013 May 27.

Abstract Mitochondria contain mtDNA derived from the ancestral endosymbiont genome. Important subunits of the oxidative phosphorylation system, which supplies cells with the energy currency...   Read More

Dysregulated autophagy contributes to podocyte damage in Fabry’s disease

publicationsLiebau MC, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller RU, Brodesser S, Saleem MA, Benzing T, Schermer B, Cybulla M, Kurschat CE; PLoS One. 2013 May 17;8(5):e63506. doi: 10.1371/journal.pone.0063506. Print 2013.

Abstract Fabry’s disease results from an inborn error of glycosphingolipid metabolism that is due to deficiency of the lysosomal hydrolase α-galactosidase A. This X-linked...   Read More

Montagna Symposium 2012: Keeping it all together–adhesion, the cytoskeleton, and signaling in morphogenesis and tissue function

A5 BRÜNING/NIESSENGreen KJ, Niessen CM, Godsel LM, Kulesz-Martin MF, J Invest Dermatol. 2013 May;133(5):1124-8. doi: 10.1038/jid.2013.59.

Pubmed

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

A11 WICKSTRÖMB3 ECKES KRIEG Radovanac K, Morgner J, Schulz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA; EMBO J. 2013 May 15;32(10):1409-24. doi: 10.1038/emboj.2013.90. Epub 2013 Apr 23.

Abstract   Integrin-linked kinase (ILK) is an adaptor protein required to establish and maintain the connection between integrins and the actin cytoskeleton. This linkage...   Read More

Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome

Brachvogel B, Zaucke F, Dave K, Norris EL, Stermann J, Dayakli M, Koch M, Gorman JJ, Bateman JF, Wilson R J. Biol. Chem. 2013...   Read More

Proteolytic processing regulates Placental growth factor activities

publicationsHoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA; J Biol Chem. 2013 Jun 21;288(25):17976-89. doi: 10.1074/jbc.M113.451831. Epub 2013 May 3.

Abstract Placental growth factor (PlGF) is a critical mediator of blood vessel formation, yet mechanisms of its action and regulation are incompletely understood. Here...   Read More

Montagna Symposium 2012: Keeping it all together–adhesion, the cytoskeleton, and signaling in morphogenesis and tissue function

A1 NIESSENA5 BRÜNING/NIESSENGreen KJ, Niessen CM, Godsel LM, Kulesz-Martin MF; J Invest Dermatol. 2013 May;133(5):1124-8. doi: 10.1038/jid.2013.59.

Pubmed

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