The innate immune system as mediator of systemic DNA damage responses

November 13, 2013A7 SCHUMACHERErmolaeva M, Schumacher B; Commun Integr Biol. 2013 Nov 13;6(6):e26926. doi: 10.4161/cib.26926. eCollection 2013.

Abstract DNA damage causally contributes to cancer development and tissue degeneration with aging.(1) Cellular DNA damage responses (DDR) mediate cell cycle arrest to allow... Read More

Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice

November 7, 2013A4 PASPARAKIS Kumari S, Bonnet MC, Ulvmar MH, Wolk K, Karagianni N, Witte E, Uthoff-Hachenberg C, Renauld JC, Kollias G, Toftgard R, Sabat R, Pasparakis M, Haase I; Immunity. 2013 Nov 14;39(5):899-911. doi: 10.1016/j.immuni.2013.10.009. Epub 2013 Nov 7.

Abstract Psoriasis is a common chronic inflammatory skin disease with a prevalence of about 2% in the Caucasian population. Tumor necrosis factor (TNF) plays... Read More

Contact

SFB 829

CECAD Research Center Joseph-Stelzmann Str. 26 D-50931 Cologne Germany

Tel: +49 221 478 895 31 Fax: +49 221 478 843 76

Monthly Archives: November 2013

The innate immune system as mediator of systemic DNA damage responses

Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice

Select

Contact

SFB 829