Abstract The ability of T cells to activate antimicrobial pathways in infected macrophages is essential to host defence against many intracellular pathogens. Here, we... Read More
Abstract Mitochondria contain mtDNA derived from the ancestral endosymbiont genome. Important subunits of the oxidative phosphorylation system, which supplies cells with the energy currency... Read More
Abstract Fabry’s disease results from an inborn error of glycosphingolipid metabolism that is due to deficiency of the lysosomal hydrolase α-galactosidase A. This X-linked... Read More
Abstract Integrin-linked kinase (ILK) is an adaptor protein required to establish and maintain the connection between integrins and the actin cytoskeleton. This linkage... Read More
Brachvogel B, Zaucke F, Dave K, Norris EL, Stermann J, Dayakli M, Koch M, Gorman JJ, Bateman JF, Wilson R J. Biol. Chem. 2013... Read More
Abstract Placental growth factor (PlGF) is a critical mediator of blood vessel formation, yet mechanisms of its action and regulation are incompletely understood. Here... Read More
Abstract We present a method in which a precise region of interest within an intact organism is spatially mapped in three dimensions by non-invasive... Read More
Villani RM, Akyuz MD, Niessen MT, Niessen CM Methods Mol. Biol. 2013;989:33-43 PMID: 23483385 Abstract The epidermis is a multilayered epithelium consisting of multiple... Read More
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