Monthly Archives: April 2014

Mechanisms regulating skin immunity and inflammation

Pasparakis M, Haase I, Nestle FO Nat. Rev. Immunol. 2014 May;14(5):289-301 PMID: 24722477 Abstract Immune responses in the skin are important for host defence...   Read More

Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo

Bazzi H, Anderson KV Proc. Natl. Acad. Sci. U.S.A. 2014 Apr;111(15):E1491-500 PMID: 24706806 Abstract Centrosomes are the microtubule-organizing centers of animal cells that organize...   Read More

Function of mammalian cell polarity regulators in skin cancer

A10 IDENMescher M, Iden S; Cell News 4/14.

Abstract Establishment of cell polarity and orchestrated tissue architecture are critical to development, organ homeostasis and regeneration. Almost every cell type in our body...   Read More

A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16

B2 WAGENER/ PAULSSON Pan TC, Zhang RZ, Arita M, Bogdanovich S, Adams SM, Gara SK, Wagener R, Khurana TS, Birk DE, Chu ML; J Biol Chem. 2014 Apr 11;289(15):10293-307. doi: 10.1074/jbc.M114.549311. Epub 2014 Feb 22.

Abstract   Dominant and recessive mutations in collagen VI genes, COL6A1, COL6A2, and COL6A3, cause a continuous spectrum of disorders characterized by muscle weakness...   Read More

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