Monthly Archives: September 2014

Proteome analysis in the assessment of ageing

A7 SCHUMACHERNkuipou-Kenfack E, Koeck T, Mischak H, Pich A, Schanstra JP, Zürbig P, Schumacher B; Ageing Res Rev. 2014 Nov;18:74-85. doi: 10.1016/j.arr.2014.09.002. Epub 2014 Sep 22.

Abstract Based on demographic trends, the societies in many developed countries are facing an increasing number and proportion of people over the age of...   Read More

Defective collagen VI α6 chain expression in the skeletal muscle of patients with collagen VI-related myopathies

B2 WAGENER/ PAULSSONTagliavini F, Pellegrini C, Sardone F, Squarzoni S, Paulsson M, Wagener R, Gualandi F, Trabanelli C, Ferlini A, Merlini L, Santi S, Maraldi NM, Faldini C, Sabatelli P; Biochim Biophys Acta. 2014 Sep;1842(9):1604-12. doi: 10.1016/j.bbadis.2014.05.033. Epub 2014 Jun 5.

Abstract Collagen VI is a non-fibrillar collagen present in the extracellular matrix (ECM) as a complex polymer; the mainly expressed form is composed of...   Read More

Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding

B12 SENGLETroilo H, Zuk AV, Tunnicliffe RB, Wohl AP, Berry R, Collins RF, Jowitt TA, Sengle G, Baldock C; Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13063-8. doi: 10.1073/pnas.1404166111. Epub 2014 Aug 25.

Abstract Bone morphogenetic proteins (BMPs) orchestrate key cellular events, such as proliferation and differentiation, in development and homeostasis. Extracellular antagonists, such as chordin, are...   Read More

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, Eftychi C, Lin J, Corona T, Hermance N, Zelic M, Kirsch P,...   Read More

Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis

A10 IDENSchlereth S, Refaian N, Iden S, Cursiefen C, Heindl; BioMed Research International. 2014:639058. Epub 2014 Sep 1

Abstract Lymphangiogenesis is a very early step in lymphatic metastasis. It is regulated and promoted not only by the tumor cells themselves, but also...   Read More

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