Yearly Archives: 2015

Mildred Scheel Lectureship series meets “Cologne Cancer Club” and “Women in Science and Society”

It was our pleasure to host the Mildred Scheel Lectureship given by Prof. Dr. Anne-Lise Børresen-Dale, University of Oslo, Norway. In cooperation with our...   Read More

hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature

Acevedo LM, Lindquist JN, Walsh BM, Sia P, Cimadamore F, Chen C, Denzel M, Pernia CD, Ranscht B, Terskikh A, Snyder EY, Cheresh DA...   Read More

Vitamin D every day to keep the infection away?

Kroner Jde C, Sommer A, Fabri M Nutrients 2015 Jun;7(6):4170-88 PMID: 26035244 Abstract Within the last decade, vitamin D has emerged as a central...   Read More

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53

publicationsDesantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M; Cell Death Dis. 2015 May 21;6:e1764. doi: 10.1038/cddis.2015.117.

Abstract The tumor suppressor p53 is mainly involved in the transcriptional regulation of a large number of growth-arrest- and apoptosis-related genes. However, a clear...   Read More

Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling

Peters F, Vorhagen S, Brodesser S, Jakobshagen K, Brüning JC, Niessen CM, Krönke M J. Invest. Dermatol. 2015 Jun;135(6):1501-9 PMID: 25705848 Abstract Ceramides are...   Read More

Reduced granulation tissue and wound strength in the absence of α11β1 integrin

B3 ECKES KRIEGSchulz JN, Zeltz C, Sørensen IW, Barczyk M, Carracedo S, Hallinger R, Niehoff A, Eckes B, Gullberg D; J Invest Dermatol. 2015 May;135(5):1435-44. doi: 10.1038/jid.2015.24. Epub 2015 Jan 29.

Abstract Previous wound healing studies have failed to define a role for either α1β1 or α2β1 integrin in fibroblast-mediated wound contraction, suggesting the involvement...   Read More

Mosaic Deficiency in Mitochondrial Oxidative Metabolism Promotes Cardiac Arrhythmia during Aging

Baris OR, Ederer S, Neuhaus JF, von Kleist-Retzow JC, Wunderlich CM, Pal M, Wunderlich FT, Peeva V, Zsurka G, Kunz WS, Hickethier T, Bunck...   Read More

Mic10 Oligomerization Pinches off Mitochondrial Cristae

publicationsMilenkovic D, Larsson NG; Cell Metab. 2015 May 5;21(5):660-1. doi: 10.1016/j.cmet.2015.04.020.

Abstract The mitochondrial contact site and cristae organizing system (MICOS) complex is essential for normal mitochondria biogenesis and morphology. In this issue, Bohnert et al....   Read More

Vitamin D controls apoptosis and proliferation of cutaneous T-cell lymphoma cells

B13 FABRIMrotzek C, Felcht M, Sommer A, Schrader A, Klemke CD, Herling M, Schlaak M, Fabri M; Exp Dermatol. 2015 May 2. doi: 10.1111/exd.12746. [Epub ahead of print]

Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms

B12 SENGLEBultmann-Mellin I, Conradi A, Maul AC, Dinger K, Wempe F, Wohl AP, Imhof T, Wunderlich FT, Bunck AC, Nakamura T, Koli K, Bloch W, Ghanem A, Heinz A, von Melchner H, Sengle G, Sterner-Kock A; Dis Model Mech. 2015 Apr;8(4):403-15. doi: 10.1242/dmm.018960. Epub 2015 Feb 20.

Abstract Recent studies have revealed an important role for LTBP-4 in elastogenesis. Its mutational inactivation in humans causes autosomal recessive cutis laxa type 1C...   Read More

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