Monthly Archives: November 2016

A1 Niessen

Regulation of epidermal morphogenesis and barrier function by intercellular junctions We have demonstrated that classical cadherins through regulation of intercellular junctions, the cytoskeleton and...   Read More

A4 Pasparakis

Epithelial TNFR1 signalling in skin homeostasis and inflammation TNF is a critical pathogenic factor in psoriasis and other chronic inflammatory diseases, but the mechanisms...   Read More

A3 Niemann

Hedgehog-Gli signalling in skin homeostasis and tumour formation Indian Hedgehog (Ihh) controls proliferation and differentiation of keratinocytes and prevents tumour progression and metastasis. Mechanistically,...   Read More

The SFB 829 has successfully renewed its consortium and will receive a further four years of funding by the German Research Foundation!

November 2016 Scientists from the medical and natural science faculty of the University of Cologne, the University Hospital, the MPI for Biology of Ageing,...   Read More

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

Lin J, Kumari S, Kim C, Van TM, Wachsmuth L, Polykratis A, Pasparakis M Nature 2016 Dec;540(7631):124-128 PMID: 27819681 Abstract Receptor-interacting protein kinase 1...   Read More

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation

Ding X, Bloch W, Iden S, Rüegg MA, Hall MN, Leptin M, Partridge L, Eming SA Nat Commun 2016 Oct;7:13226 PMID: 27807348 Abstract Mammalian...   Read More

The role of Rho kinase (Rock) in re-epithelialization of adult zebrafish skin wounds

Richardson R, Hammerschmidt M Small GTPases 2018 05;9(3):230-236 PMID: 27487414 Abstract Complete re-epithelialization of full-thickness skin wounds in adult mammals takes days to complete...   Read More

© 2017 SFB 829

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