Yearly Archives: 2018

Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA protease FtsH

Uthoff M, Baumann U J. Struct. Biol. 2018 Nov;204(2):199-206 PMID: 30118817 Abstract Two crystal structures of a transmembrane helix-lacking FtsH construct from Aquifex aeolicus...   Read More

Glucocorticoids promote intrinsic human T17 differentiation

de Castro Kroner J, Knoke K, Kofler DM, Steiger J, Fabri M J. Allergy Clin. Immunol. 2018 Nov;142(5):1669-1673.e11 PMID: 30092286 Abstract

Pioneering of Enhancer Landscapes during Pluripotent State Transitions

Rada-Iglesias A Cell Stem Cell 2018 Aug;23(2):149-151 PMID: 30075122 Abstract The transitions between different pluripotency states are regulated by large changes in enhancer landscapes....   Read More

Signaling in the stem cell niche: regulating cell fate, function and plasticity

Chacón-Martínez CA, Koester J, Wickström SA Development 2018 08;145(15) PMID: 30068689 Abstract Stem cells have the ability to self-renew and differentiate along multiple lineages,...   Read More

Preparing junior faculty for success

Sawarkar R, Scherz-Shouval R, Denzel M, Saarikangas J Science 2018 07;361(6399):238 PMID: 30026218 Abstract

Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program

Do NN, Willenborg S, Eckes B, Jüngst C, Sengle G, Zaucke F, Eming SA J. Immunol. 2018 Jul;201(2):663-674 PMID: 29898959 Abstract Myeloid cells can...   Read More

E-cadherin binds to desmoglein to facilitate desmosome assembly

Shafraz O, Rübsam M, Stahley SN, Caldara AL, Kowalczyk AP, Niessen CM, Sivasankar S Elife 2018 07;7 PMID: 29999492 Abstract Desmosomes are adhesive junctions...   Read More

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas

Kunz M, Löffler-Wirth H, Dannemann M, Willscher E, Doose G, Kelso J, Kottek T, Nickel B, Hopp L, Landsberg J, Hoffmann S, Tüting T,...   Read More

Nuclear Genomic Instability and Aging

Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD Annu. Rev. Biochem. 2018 06;87:295-322 PMID: 29925262 Abstract The nuclear genome decays...   Read More

Cell adhesion and mechanics as drivers of tissue organization and differentiation: local cues for large scale organization

Wickström SA, Niessen CM Curr. Opin. Cell Biol. 2018 10;54:89-97 PMID: 29864721 Abstract Biological patterns emerge through specialization of genetically identical cells to take...   Read More

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