Tissue fibrosis: a pathomechanistically unresolved challenge and scary clinical problem

Eckes B, Eming SA Exp. Dermatol. 2016 Aug; PMID: 27513440 Abstract Fibrosis is defined as the replacement of healthy tissue by an excessive deposition...   Read More

Proplatelet formation is selectively inhibited by collagen type I via Syk-independent GPVI signaling

Semeniak D, Kulawig R, Stegner D, Meyer I, Schwiebert S, Bösing H, Eckes B, Nieswandt B, Schulze H J. Cell. Sci. 2016 Aug; PMID:...   Read More

Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

Strilic B, Yang L, Albarrán-Juárez J, Wachsmuth L, Han K, Müller UC, Pasparakis M, Offermanns S Nature 2016 08;536(7615):215-8 PMID: 27487218 Abstract Metastasis is...   Read More

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

Le HQ, Ghatak S, Yeung CY, Tellkamp F, Günschmann C, Dieterich C, Yeroslaviz A, Habermann B, Pombo A, Niessen CM, Wickström SA Nat. Cell...   Read More

Essential role of polarity protein Par3 for epidermal homeostasis through regulation of barrier function, keratinocyte differentiation and stem cell maintenance

Ali NJ, Dias Gomes M, Bauer R, Brodesser S, Niemann C, Iden S J. Invest. Dermatol. 2016 Jul; PMID: 27452221 Abstract Partitioning-defective (Par) proteins...   Read More

Image of SFB 829 PI Gerhard Sengle on the Cover of the Journal of Investigative Dermatology

                        This image was published in JID, Vol 136, Gerhard Sengle, Copyright Elsevier,...   Read More

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

Hatzold J, Beleggia F, Herzig H, Altmüller J, Nürnberg P, Bloch W, Wollnik B, Hammerschmidt M Elife 2016 May;5 PMID: 27240166 Abstract Molecular pathways...   Read More

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T,...   Read More

Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages

Steiger J, Stephan A, Inkeles MS, Realegeno S, Bruns H, Kröll P, de Castro Kroner J, Sommer A, Batinica M, Pitzler L, Kalscheuer R,...   Read More

Epidermal NLRP10 contributes to contact hypersensitivity responses in mice

Damm A, Giebeler N, Zamek J, Zigrino P, Kufer TA Eur. J. Immunol. 2016 May; PMID: 27221772 Abstract The NLR protein NLRP10 is highly...   Read More

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