Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes

Aatsinki SM, Elkhwanky MS, Kummu O, Karpale M, Buler M, Viitala P, Rinne V, Mutikainen M, Tavi P, Franko A, Wiesner RJ, Chambers KT,...   Read More

Leucurogin and melanoma therapy

Almeida MC, Santos IC, Paschoalin T, Travassos LR, Mauch C, Zigrino P, Pesquero JB, Pesquero JL, Higuchi DA Toxicon 2019 Mar;159:22-31 PMID: 30611825 Abstract...   Read More

Epithelial polarity limits EMT

Persa OD, Niessen CM Nat. Cell Biol. 2019 Mar;21(3):299-300 PMID: 30824839 Abstract Epithelial–mesenchymal transition (EMT) is crucial for development, and for dissemination and invasion...   Read More

SFB Guest Scientist Dr. Scott Williams, from The University of North Carolina at Chapel Hill

Dr. Williams´ lab is interested in studying how asymmetric cell division of skin progenitors is controlled at a molecular level, and how division orientation impacts cell...   Read More

The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival

Ayachi O, Barlin M, Broxtermann PN, Kashkar H, Mauch C, Zigrino P Cell Oncol (Dordr) 2019 Feb; PMID: 30778852 Abstract BACKGROUND: The X-linked inhibitor...   Read More

Augmented contractility of murine femoral arteries in a streptozotocin diabetes model is related to increased phosphorylation of MYPT1

Lubomirov LT, Gagov H, Schroeter MM, Wiesner RJ, Franko A Physiol Rep 2019 Feb;7(3):e13975 PMID: 30740930 Abstract Diabetes mellitus (DM) is a metabolic disorder...   Read More

IFN-γ Promotes, but Dexamethasone Dissociates, Toll-Like Receptor 2/1-Induced Host Responses in Human Macrophages

Kröll P, Knoke K, Steiger J, Fabri M J. Invest. Dermatol. 2019 Feb;139(2):488-491 PMID: 30193757 Abstract

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C,...   Read More

Phase-specific functions of macrophages determine injury-mediated corneal hem- and lymphangiogenesis

Kiesewetter A, Cursiefen C, Eming SA, Hos D Sci Rep 2019 Jan;9(1):308 PMID: 30670724 Abstract Macrophages are critical mediators of injury-associated corneal hemangiogenesis (HA)...   Read More

Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics

Denzel MS, Lapierre LR, Mack HID Mech. Ageing Dev. 2019 01;177:4-21 PMID: 30134144 Abstract Key discoveries in aging research have been made possible with...   Read More

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