Abstract The hexameric membrane-spanning ATP-dependent metalloprotease FtsH is universally conserved in eubacteria, mitochondria, and chloroplasts, where it fulfills key functions in quality control and... Read More
Blumbach K, Bastiaansen-Jenniskens YM, DeGroot J, Paulsson M, van Osch GJ, Zaucke F Arthritis Rheum. 2009 Dec;60(12):3676-85 PMID: 19950300 Abstract OBJECTIVE: Defects in the... Read More
Bazzi H, Demehri S, Potter CS, Barber AG, Awgulewitsch A, Kopan R, Christiano AM Differentiation 2009 Dec;78(5):292-300 PMID: 19683850 Abstract The hair fiber is... Read More
Abstract During blood vessel development, vascular smooth muscle cells (vSMCs) and pericytes (PCs) are recruited to nascent vessels to stabilize them and to guide... Read More
Abstract The development of multicellular organisms requires integrin-mediated interactions between cells and their extracellular environment. Integrin binding to extracellular matrix catalyses assembly of multiprotein... Read More
Abstract Recent discoveries have revealed the importance of the vitamin D-dependent generation of antimicrobial peptides in human host defense against Mycobacterium tuberculosis. Now, Yuk... Read More
Abstract The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin... Read More
Abstract Endorepellin, the C-terminal domain of perlecan, is a powerful angiogenesis inhibitor. To dissect the mechanism of endorepellin-mediated endothelial silencing, we used an antibody... Read More
Abstract The aberrant expression of the transmembrane protein EpCAM is associated with tumor progression, affecting different cellular processes such as cell-cell adhesion, migration, proliferation,... Read More
Abstract Osteogenesis imperfecta (OI) is a hereditary disease occurring in humans and dogs. It is characterized by extremely fragile bones and teeth. Most human... Read More
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