Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations

Irmak D, Fatima A, Gutiérrez-Garcia R, Rinschen MM, Wagle P, Altmüller J, Arrigoni L, Hummel B, Klein C, Frese CK, Sawarkar R, Rada-Iglesias A,...   Read More

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin

Singh K, Camera E, Krug L, Basu A, Pandey RK, Munir S, Wlaschek M, Kochanek S, Schorpp-Kistner M, Picardo M, Angel P, Niemann C,...   Read More

Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA protease FtsH

Uthoff M, Baumann U J. Struct. Biol. 2018 Nov;204(2):199-206 PMID: 30118817 Abstract Two crystal structures of a transmembrane helix-lacking FtsH construct from Aquifex aeolicus...   Read More

Glucocorticoids promote intrinsic human T17 differentiation

de Castro Kroner J, Knoke K, Kofler DM, Steiger J, Fabri M J. Allergy Clin. Immunol. 2018 Nov;142(5):1669-1673.e11 PMID: 30092286 Abstract

Pioneering of Enhancer Landscapes during Pluripotent State Transitions

Rada-Iglesias A Cell Stem Cell 2018 Aug;23(2):149-151 PMID: 30075122 Abstract The transitions between different pluripotency states are regulated by large changes in enhancer landscapes....   Read More

Signaling in the stem cell niche: regulating cell fate, function and plasticity

Chacón-Martínez CA, Koester J, Wickström SA Development 2018 08;145(15) PMID: 30068689 Abstract Stem cells have the ability to self-renew and differentiate along multiple lineages,...   Read More

Preparing junior faculty for success

Sawarkar R, Scherz-Shouval R, Denzel M, Saarikangas J Science 2018 07;361(6399):238 PMID: 30026218 Abstract

Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program

Do NN, Willenborg S, Eckes B, Jüngst C, Sengle G, Zaucke F, Eming SA J. Immunol. 2018 Jul;201(2):663-674 PMID: 29898959 Abstract Myeloid cells can...   Read More

E-cadherin binds to desmoglein to facilitate desmosome assembly

Shafraz O, Rübsam M, Stahley SN, Caldara AL, Kowalczyk AP, Niessen CM, Sivasankar S Elife 2018 07;7 PMID: 29999492 Abstract Desmosomes are adhesive junctions...   Read More

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas

Kunz M, Löffler-Wirth H, Dannemann M, Willscher E, Doose G, Kelso J, Kottek T, Nickel B, Hopp L, Landsberg J, Hoffmann S, Tüting T,...   Read More

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