The cartilage-specific lectin C-type lectin domain family 3 member A (CLEC3A) enhances tissue plasminogen activator-mediated plasminogen activation

Lau D, Elezagic D, Hermes G, Mörgelin M, Wohl AP, Koch M, Hartmann U, Höllriegl S, Wagener R, Paulsson M, Streichert T, Klatt AR...   Read More

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

Nüchel J, Ghatak S, Zuk AV, Illerhaus A, Mörgelin M, Schönborn K, Blumbach K, Wickström SA, Krieg T, Sengle G, Plomann M, Eckes B...   Read More

Although Abundant in Tumor Tissue, Mast Cells Have No Effect on Immunological Micro-milieu or Growth of HPV-Induced or Transplanted Tumors

Ghouse SM, Polikarpova A, Muhandes L, Dudeck J, Tantcheva-Poór I, Hartmann K, Lesche M, Dahl A, Eming S, Müller W, Behrendt R, Roers A...   Read More

Is H3K4me1 at enhancers correlative or causative?

Rada-Iglesias A Nat. Genet. 2018 Jan;50(1):4-5 PMID: 29273804 Abstract

STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo

Bazzi H, Soroka E, Alcorn HL, Anderson KV Proc. Natl. Acad. Sci. U.S.A. 2017 12;114(51):E10928-E10936 PMID: 29203676 Abstract Regulated mesoderm migration is necessary for...   Read More

ERC Advanced Grant for Manolis Pasparakis

The European Research Council (ERC) awarded one of its highest personal awards to the SFB 829 project leader Manolis Pasparakis. The award is endowed with...   Read More

Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model

La Fata G, van Vliet N, Barnhoorn S, Brandt RMC, Etheve S, Chenal E, Grunenwald C, Seifert N, Weber P, Hoeijmakers JHJ, Mohajeri MH,...   Read More

Trichothiodystrophy causative TFIIEβ mutation affects transcription in highly differentiated tissue

Theil AF, Mandemaker IK, van den Akker E, Swagemakers SMA, Raams A, Wüst T, Marteijn JA, Giltay JC, Colombijn RM, Moog U, Kotzaeridou U,...   Read More

Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging

Edifizi D, Schumacher B Int J Mol Sci 2017 Nov;18(11) PMID: 29113067 Abstract DNA damage causally contributes to aging and age-related diseases. The declining...   Read More

DNA damage responses and p53 in the aging process

Ou HL, Schumacher B Blood 2017 Nov; PMID: 29141944 Abstract The genome is constantly attacked by genotoxic insults. DNA damage has long been established...   Read More

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