SFB Guest Scientist Dr. Scott Williams, from The University of North Carolina at Chapel Hill

Dr. Williams´ lab is interested in studying how asymmetric cell division of skin progenitors is controlled at a molecular level, and how division orientation impacts cell fate choices in normal and neoplastic growth. To facilitate these and other studies in diverse epithelia, his lab has developed a powerful functional tool, in utero lentiviral RNAi, which allows them to rapidly perform functional studies on any gene in the intact mouse in weeks instead of years. Their broad goal is to use this technique, in combinations of candidate and screening approaches, to dissect pathways that influence epithelial differentiation. Beyond studying how division orientation influences epidermal development, his lab also studies the role that the spindle orientation complex plays in other tissues, including the cerebellum and oral epithelia. In addition, they have broad interests in studying the mechanisms that control the formation and maintenance of stratified epithelia in the context of development, stem cell function, and disease.

From the 17th to the 22nd of March, we will have Dr. Scott Williams, from The University of North Carolina at Chapel Hill, as guest at the University of Cologne. On the 20th of March, at 4pm, he will give a SFB seminar in the CECAD Lecture Hall with the title “Generation and maintenance of stratified epithelia.”

Link to SFB seminar by Scott Williams

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